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Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery

Recruitingn/aAges 18 Years - 75 YearsAllSehit Prof. Dr. Ilhan Varank Sancaktepe Training …
NCT07862257 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under general anesthesia. Cerebral regional oxygen saturation will be monitored using bilateral frontal near-infrared spectroscopy (NIRS), while respiratory parameters including tidal volume, respiratory rate, peak airway pressure, plateau pressure, positive end-expiratory pressure, and dynamic compliance will be recorded from the anesthesia ventilator. Measurements will be obtained at predefined time points before and after positioning the patient prone and after returning to the supine position at the end of surgery. No changes will be made to anesthesia, ventilation, medication doses, or surgical management for research purposes. All clinical care will be provided accor

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-75 years * Written informed consent * Scheduled for elective lumbar disc herniation surgery * ASA physical status I-III * Volume-controlled ventilation Exclusion Criteria: * History of increased intracranial pressure * Conditions preventing placement of cerebral NIRS probes * Development of severe intraoperative complications * Significant hemodynamic instability * Known cerebrovascular disease or severe carotid artery disease * Hemoglobin \<10 g/dL or anticipated major bleeding * Severe heart failure (EF \<40%) * Advanced COPD or restrictive lung disease * Orthopedic or neurological conditions preventing tolerance of the prone position
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What it tests

  • Prone Positioning
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Where

1 site
Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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