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Basal LH Threshold for the Diagnosis of Central Precocious Puberty

Recruitingn/aAges 4 Years - 11 YearsAllUniversity Hospital, Strasbourg, France
NCT07864116 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This retrospective monocentric observational study aims to evaluate whether basal luteinizing hormone (LH) levels can reliably diagnose central precocious puberty and reduce the need for LHRH stimulation testing. Currently, all patients with suspected precocious puberty undergo LHRH testing regardless of basal LH levels. The study will analyze pediatric patients evaluated between 2019 and 2024 to determine an optimal basal LH threshold with high specificity. Secondary analyses will assess diagnostic performance and explore clinical and biological factors influencing LH levels. The results may help reduce unnecessary testing and improve diagnostic strategies.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Children aged 4 to 11 years * Underwent LHRH stimulation testing for suspected precocious puberty between 01/01/2019 and 01/01/2024 * No written opposition to reuse of medical data Exclusion Criteria: * Written opposition to data reuse * Age \<4 years or \>11 years 11 months * LHRH test performed for indications other than suspected precocious puberty
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What it tests

  • Not listed
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Where

1 site
Service de Pédiatrie 1 - CHU de Strasbourg - France
Strasbourg, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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