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Prevalence of Adrenal Insufficiency and Associated Factors in Rheumatoid Arthritis Patients Using Low-dose Corticosteroids.

Recruitingn/aAges 18 Years - 65 YearsAllBursa Yuksek Ihtisas Training and Research Hospit…
NCT07866326 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to investigate the prevalence of adrenal insufficiency in rheumatoid arthritis (RA) patients receiving low-dose corticosteroid therapy and to identify the factors influencing adrenal insufficiency. To this end, the researchers plan to conduct a study comparing the prevalence of adrenal insufficiency and associated factors among RA patients-who are currently receiving low-dose corticosteroid therapy during outpatient follow-up and have consented to participate-by categorizing them into three groups based on the duration of treatment: short (3 weeks-3 months), medium (3-12 months), and long (\>12 months).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participants diagnosed with rheumatoid arthritis according to the 2010 ACR/EULAR criteria. * Participants who have been undergoing corticosteroid treatment for at least 3 weeks. * Participants in remission or with low disease activity (DAS28-CRP ≤3.2). Exclusion Criteria: * Patients with primary adrenal insufficiency. * Participants who have received pulse steroid therapy within the last 6 months. * Pregnancy and lactation. * Hypopituitarism * Uncontrolled diabetes mellitus * Comorbidities; ≥NYHA Class 3 heart failure, Stage 3 chronic kidney failure, ≥Child-Pugh Class B liver cirrhosis
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What it tests

  • ACTH stimulation test
  • Cortisol
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Where

1 site
SBU Bursa Yüksek İhtisas EAH
Bursa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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