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In recent years, experimental and clinical studies conducted on sheep tail fat, a natural and easily accessible resource, have shown that bioactive components found in sheep tail fat, such as palmitic acid, stearic acid, oleic acid, linoleic acid, and myristic acid, have anti-inflammatory and chondroprotective (cartilage-protective) properties. In addition, literature reviews have revealed that sheep tail fat alleviates joint pain and has a positive effect on joint stiffness. Sheep tail fat is known to be frequently used by patients with gonarthrosis (knee osteoarthritis) in Türkiye and many other countries as a traditional and complementary medicine method. In this context, this study is designed as a randomized controlled experimental study to evaluate the effects of sheep tail fat application on pain, joint stiffness, and activities of daily living in patients with gonarthrosis. The
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