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Effects of Alternate Nostril Breathing Versus Diaphragmatic Breathing on Oxygen Saturation and Heart-rate Variability in Post Percutaneous Coronary Intervention Patients

RecruitingNAAges 44 Years - 75 YearsAllFoundation University Islamabad
NCT07867457 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a two-arm randomized parallel group trial designed to compare the effects of alternate nostril breathing vs diaphragmatic breathing on oxygen saturation and Heart-rate variability in hemodynamically stable post-PCI patients. Participants will be randomly allocated in a 1:1 ratio to alternate nostril breathing or diaphragmatic breathing and will receive the allocated intervention for 2 consecutive days with three supervised sessions per day in addition to routine post-PCI care. Oxygen saturation will be assessed using a pulse oximeter and heart-rate variability will be assessed using a Polar H10 sensor at baseline and after the intervention. The study will determine whether there is a difference between two breathing interventions in the prescribed outcome measures.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 44-75 years * Hemodynamically stable post-PCI patients with systolic blood pressure\>90 mmHg, diastolic BP 50-100mmHg Heart-rate 60-100 beats/min and no ongoing chest pain or signs of acute clinical instability. * Oxygen saturation \>92% on room air * Able to follow simple verbal instructions and perform the breathing exercises. * Ejection Fraction \>35% Exclusion Criteria: * Ongoing myocardial ischemia, unstable angina, significant arrythmia or requirement for inotropic/vasopressor support. * Cardiogenic shock or severe heart failure (NYHA class IV) * Recent thoracic surgery or chest wall injury limiting rib expansion or deep breathing. * Cardiac implantable electronic device (pacemaker/ICD) with pacing dependency or an implanted ventricular assist device. * Severe cognitive impairment * Uncontrolled hypertension(SBP\>180 mmHg or DBP\>110 mmHg) or bradycardia\<50 beats/min. * Severe anemia (Hb\<8g/dL)
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What it tests

  • Alternate Nostril Breathing
  • Diaphragmatic breathing
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Where

1 site
Foundation University Islamabad
Rawalpindi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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