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Follicular Flushing Versus Direct Aspiration in Transabdominal Oocyte Retrieval

Recruitingn/aAges 18 Years - 42 YearsFemaleCentrum Clinic IVF Center
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn whether rinsing the egg sacs (follicles) during egg collection helps doctors collect more eggs in women with low egg reserve. Participants are unmarried women aged 18 to 42 who are freezing their eggs and who chose to have eggs collected through the abdomen instead of the vagina. Low egg reserve means a blood level of anti-Müllerian hormone (AMH) of 1 ng/mL or lower. The main questions it aims to answer are: Does rinsing the follicles raise the total number of eggs collected? Does rinsing the follicles raise the number of mature eggs that can be frozen? Researchers will compare two egg collection methods, each used routinely at one of two IVF centres in Turkey: Direct aspiration: each follicle is emptied once with a single-channel needle, with no rinsing. Follicular flushing: a double-channel needle is used. If no egg is found after t

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📋 Eligibility rules (as published)
IEligibility Criteria Inclusion Criteria: * Women aged 18-42 years * Serum anti-Müllerian hormone (AMH) ≤1.0 ng/mL * Planned oocyte cryopreservation for fertility preservation * Decline of transvaginal oocyte retrieval for cultural or personal reasons, with transabdominal retrieval chosen as the preferred route * Eligible for oocyte cryopreservation under Turkish regulations * At least one follicle ≥17 mm on the day of ovulation trigger * Written informed consent Exclusion Criteria: * Conditions that prevent safe transabdominal access, such as extensive pelvic adhesions or unfavourable ovarian position * Previous major abdominal or pelvic surgery likely to interfere with the procedure * Active pelvic infection * Suspected ovarian malignancy * Contraindications to sedation or oocyte retrieval * Retrieval performed outside local regulatory requirements * Incomplete clinical or laboratory data
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What it tests

  • Not listed
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Where

2 sites
Centrum Clinic IVF Center
Ankara, Turkey (Türkiye)
Brussels IVF Center
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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