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Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery

RecruitingNAAges 18 Years - anyAllBucharest Emergency Hospital
NCT07881133 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery. The study is a randomized controlled trial conducted at Bucharest Emergency Clinical Hospital, Romania. Participants are assigned to either an intervention group receiving enhanced recovery care (ERAS) combined with perioperative biomarker monitoring or a control group receiving standard postoperative care. The biomarkers of interest include procalcitonin, lactate, and blood glucose. The study will examine their relationship with postoperative complications, particularly infections and anastomotic leakage. Participants will be followed for 30 days after surgery to assess postoperative complications, hospital length of stay, readmissions, and mortality. The findings may

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients aged 18 years or older. * Patients diagnosed with colorectal or gastric cancer. * Patients scheduled for elective abdominal oncologic surgery. * Patients classified as ASA physical status II-IV. * Patients who provide written informed consent to participate in the study. Exclusion Criteria: * Patients with known autoimmune or immunological diseases that may significantly influence inflammatory biomarker levels. * Patients diagnosed with inflammatory bowel disease (IBD). * Patients who refuse to participate or do not provide written informed consent.
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What it tests

  • Perioperative Biomarker-Guided Monitoring
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Where

1 site
Emergency Clinical Hospital Bucharest
Bucharest, Romania
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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