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This randomized clinical trial will compare the effectiveness of liquid nitrogen cryotherapy and carbon dioxide (CO₂) laser therapy for treating palmoplantar warts, which are human papillomavirus-related skin growths occurring on the palms and soles. The main question the study aims to answer is: \- Does CO₂ laser therapy achieve complete wart clearance more frequently than liquid nitrogen cryotherapy after 12 weeks of treatment? The study will include 88 adults aged 18-50 years with palmoplantar warts. Participants will be randomly assigned to one of two treatment groups: * Group A: Liquid nitrogen cryotherapy at -196°C, using two freeze-thaw cycles once weekly for up to 8 weeks. * Group B: CO₂ laser therapy administered weekly for up to 8 weeks. Participants will be assessed at week 12 after treatment initiation by a consultant dermatologist who will not know which treatment they
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