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Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty

Recruitingn/aAges 18 Years - anyAllBalikesir Ataturk City Hospital
NCT07882316 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational cohort study aims to investigate the association between preoperative multimorbidity burden and functional recovery after primary total knee arthroplasty (TKA) in patients with knee osteoarthritis. Approximately 230 adult patients undergoing elective unilateral primary TKA will be enrolled at a single hospital in Türkiye. Preoperative multimorbidity burden will be assessed using the Functional Comorbidity Index (FCI), which measures the presence of medical conditions that may affect physical function. Patients will be evaluated before surgery and at 6 and 12 months after surgery. Functional outcomes and pain will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Oxford Knee Score (OKS). Anxiety and depressive symptoms will be evaluated using the Hospital Anxiety and Depression Scale (HADS). The primary objec

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years or older. * Scheduled for elective unilateral primary total knee arthroplasty due to primary knee osteoarthritis. * Sufficient cognitive and communication abilities to understand and complete the study questionnaires. * Provision of written informed consent for study participation. Exclusion Criteria: * Patients scheduled for revision total knee arthroplasty. * Patients scheduled for simultaneous bilateral total knee arthroplasty. * Arthroplasty indicated for inflammatory arthritis, tumor, infection, or post-traumatic conditions. * Severe cognitive impairment, advanced dementia, or communication difficulties preventing valid completion of the study questionnaires. * Significant logistical or legal circumstances preventing completion of the planned follow-up assessments.
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What it tests

  • Not listed
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Where

1 site
Güneş Sarikaya
Balıkesir, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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