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Postoperative Pain Trajectories After Endometriosis Surgery

Recruitingn/aAges 18 Years - anyFemaleCentre Hospitalier Universitaire, Amiens
NCT07882498 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The pain associated with endometriosis reflects a multifactorial pathophysiology combining peripheral nociception, central sensitisation and psychosocial factors. Although surgery is an integral part of treatment, a significant proportion of patients experience persistent pain several months after the procedure. To date, postoperative pain trajectories after endometriosis surgery remain poorly characterised, and there are no reliable predictors of chronic postoperative pain (CPP). This prospective, single-centre, longitudinal study aims to identify distinct postoperative pain trajectories and to assess whether perioperative quantitative sensory testing can predict the development of chronic postoperative pain at 3 and 6 months. Patients will undergo perioperative mechanical and pressure tests, including assessment of temporal summation and pressure pain thresholds, combined with validate

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Imaging-confirmed endometriosis * Scheduled surgical treatment for endometriosis * Affiliation to the French Social Security system * Written informed consent obtained Exclusion Criteria: * Patients under legal protection (guardians or curators) * History of psychiatric disorders * Neurodegenerative diseases * Inability to self-assess pain using a numerical rating scale * Non-French-speaking patients * Pregnancy or breastfeeding * Refusal to participate
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What it tests

  • Perioperative quantitative sensory testing
  • questionnaire
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Where

1 site
CHU Amiens-Picardie
Amiens, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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