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Comparison of Operative Hysteroscopy and Vacuum Aspiration for Terminating First-trimester Pregnancy With Intrauterine Adhesions

Recruitingn/aAges 18 Years - 40 YearsFemaleWomen's Hospital School Of Medicine Zhejiang Univ…
NCT07883057 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In cases of early pregnancy complicated with intrauterine adhesions (IUAs), termination of pregnancy is prone to incomplete abortion with retained gestational products, failed abortion or uterine perforation due to altered uterine cavity structure and gestational sac obscured by adhesive bands. Reoperation may even be required, which increases the risk of surgical trauma, as well as the psychological and financial burdens on patients. Meanwhile, some patients with IUAs still have fertility demands in the future, so the adhesions also need to be addressed. Hysteroscopy allows direct visualization to remove intrauterine gestational contents, lowering the risks of tissue retention and reoperation. It also enables concurrent treatment of existing IUAs. Combined with postoperative interventions to prevent adhesion recurrence, this approach can restore the uterine cavity structure and endomet

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. patients with transvaginal ultrasound findings suggestive of IUA; 2. patients who underwent follow-up postoperative ultrasound examinations for 3 or more months at the study hospital; 3. patients with a desire to bear children; 4. patients with no significant organic diseases. Exclusion Criteria: 1. patients with ectopic pregnancies, e.g., a cesarean scar pregnancy, angular pregnancies, or a cervical pregnancy; 2. patients who underwent other intrauterine surgical procedures, such as endometrial polypectomy, submucosal myomectomy, or uterine septum resection, during hysteroscopy; 3. patients who underwent medical termination of pregnancy with oral mifepristone plus misoprostol without surgery; 4. patients with abnormal postoperative pathological results, e.g., molar pregnancy; 5. patients without follow-up data or ultrasound results or with incomplete data for 3 months after surgery; 6. patients whose initial surgery was not performed at the study hospital.
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What it tests

  • Vacuum Aspiration Group
  • Hysteroscopy adhesiolysis combined with vacuum aspiration
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Where

1 site
Women's Hospital, Zhejiang University School of Medicine
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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