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Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG

Recruitingn/aAges 18 Years - 100 YearsAllXin Lou
NCT07883499 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to learn whether information about heart muscle tissue from preoperative photon-counting CT, a newer type of CT scan, can help predict heart recovery 3 months after coronary artery bypass surgery. The study will include adults aged 18 years or older with coronary artery disease who are scheduled for coronary artery bypass surgery without another major heart operation. The main question it aims to answer is: \- Can heart muscle information from CT before surgery help predict the amount of blood remaining in the heart's left pumping chamber after it contracts, adjusted for body size, 3 months after surgery? This measurement is called the left ventricular end-systolic volume index and will be used to assess early changes in heart structure after surgery. Participants will: * Have photon-counting CT scans and heart ultrasound examinations before su

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥18 years and scheduled for isolated CABG. 2. Able to undergo the protocol-specified PCCT examinations after assessment by the clinical and imaging teams. 3. Able to understand the study and provide written informed consent, and willing to attend the 3-month postoperative follow-up. Exclusion Criteria: 1. Planned concomitant major cardiac surgery, such as valve or aortic surgery, that places the patient outside the target population of isolated CABG. 2. A clinically assessed contraindication to contrast-enhanced CT, including a severe iodinated contrast allergy that cannot be adequately managed, pregnancy, or another examination contraindication. 3. Clinical condition precluding research examinations, or a research workflow that could delay necessary treatment. 4. Unable to complete the informed consent process or explicitly unwilling to attend the required follow-up.
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What it tests

  • Not listed
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Where

1 site
Department of Radiology, the First Medical Center of Chinese PLA General Hospital/ Chinese PLA Medical School, Beijing, China
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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