🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Prospective Comparison of Pro-Adrenomedullin, C-Reactive Protein, and Neutrophil-to-Lymphocyte Ratio for Diagnosing Acute Appendicitis

Recruitingn/aAges 18 Years - 90 YearsAllBursa Yuksek Ihtisas Training and Research Hospit…
NCT07889544 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this prospective observational study is to evaluate the diagnostic accuracy of pro-adrenomedullin (Pro-ADM) in adults with acute appendicitis and compare its performance with conventional inflammatory biomarkers, particularly C-reactive protein (CRP) and the neutrophil-to-lymphocyte ratio (NLR). The main questions are: * How accurately can Pro-ADM distinguish patients with acute appendicitis from healthy controls? * How does the diagnostic performance of Pro-ADM compare with that of CRP and NLR? * Can Pro-ADM help predict complicated acute appendicitis? Researchers will compare adults undergoing appendectomy for acute appendicitis with healthy individuals attending outpatient clinics for routine evaluations. Participants will: * Provide information about their medical history and clinical characteristics. * Undergo blood sampling for Pro-ADM measurement. * Have relevant r

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. Adults aged 18 to 90 years. 2. Patients presenting to the emergency department within 48 hours of the onset of abdominal pain, either directly or following referral from another healthcare institution with a diagnosis or suspicion of acute appendicitis. 3. Patients undergoing appendectomy for acute appendicitis (acute appendicitis group). 4. Individuals attending outpatient clinics for routine health evaluations without abdominal pain or active inflammatory disease (control group). 5. Provision of informed consent for participation in the study. Exclusion Criteria: 1. Age younger than 18 years or older than 90 years. 2. Use of antibiotics or systemic corticosteroids within the preceding month. 3. Active malignancy. 4. Immunosuppressive disease or ongoing immunosuppressive treatment. 5. Abdominal surgery within the preceding three months. 6. Heart failure, renal failure, or liver cirrhosis. 7. Pregnancy or postpartum period. 8. Inability to provide informed consent due to psychiatric disorders.
💊

What it tests

  • Serum Pro-Adrenomedullin Measurement
📍

Where

1 site
Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy