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Integrated Assessment of Immune-Inflammatory and Metabolic Biomarkers for Prediction of Coronary No-Reflow Following Primary PCI in STEMI Patients

Recruitingn/aAges 18 Years - anyAllSohag University
NCT07890168 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the combined predictive value of immune-inflammatory and metabolic biomarkers for coronary no-reflow following primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI), with the goal of improving early risk stratification and clinical decision-making.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years old. * Both sexes. * Diagnosis of ST-segment elevation myocardial infarction (STEMI) according to current ESC/ACC guidelines. * Presentation within 12 hours of symptom onset. * Undergoing primary percutaneous coronary intervention (PCI) as the reperfusion strategy. Exclusion Criteria: * Active infection or sepsis. * Chronic inflammatory or autoimmune diseases. * Hematological disorders. * Active malignancy. * Severe liver disease. * End-stage renal disease requires dialysis. * Previous coronary artery bypass graft surgery (CABG). * Current use of chronic corticosteroid or immunosuppressive therapy.
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What it tests

  • Assessment of immune-inflammatory and metabolic biomarkers
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Where

1 site
Sohag University
Sohag, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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