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Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery

RecruitingNAAges 18 Years - anyAllSemmelweis University
NCT07896174 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions. The main questions it aims to answer are: * Does resistance (strength) training, aerobic (endurance) training, or a combination of both before surgery lower the rate and severity of complications in the first 30 days after surgery, compared with no exercise program? * Which factors influence how well patients follow a prehabilitation program, and does following the program affect surgical outcomes? Researchers will compare three exercise groups with a control group that receives standard care without an exercise program. Participants will: * Be randomly assigned to one of four groups: resistance training, aerobic training, combined training, or no exercise program (control) * Do the assigned hom

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age over 18 years * Elective, curative-intent colon or rectal resection * Malignant or premalignant colorectal lesion * Signed written informed consent after receiving study information Exclusion Criteria: * Refusal to participate in the study * Comorbidities precluding physical prehabilitation * Physical, neurological or mental status precluding physical prehabilitation * Unplanned acute surgery required during the prehabilitation period * Transanal minimally invasive surgery (TAMIS) * Palliative surgery only * Pregnancy * Preoperative preparation program deviating from the study protocol, as deemed necessary by the study team
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What it tests

  • Resistance Training Prehabilitation
  • Aerobic Training Prehabilitation
  • Standard Trimodal Care
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Where

1 site
Semmelweis University, Department of Surgery, Transplantation and Gastroenterology
Budapest, Hungary
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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