AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Evaluation of Crisaborole 2% Versus Tacrolimus 0.1% Each Combined With Excimer Light in the Treatment of Stable Non-segmental Facial Vitiligo: a Prospective Randomized Controlled Study.

RecruitingPhase 3Ages 6 Years - anyAllCairo University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if topical application of crisaborole 2% ointment can treat stable patches of facial vitiligo in pediatrics and adult patients of both genders. It will also learn about the safety of crisaborole 2% ointment. The main questions it aims to answer is: * Does crisaborole 2% ointment work effectively in stable localized facial vitiligo in pediatrics and adults? * is crisaborole 2% ointment well tolerated in stable localized facial vitiligo in pediatrics and adults? * Is crisaborole 2% ointment comparable to tacrolimus 0.1% ointment in terms of efficacy and safety in stable localized facial vitiligo in pediatrics and adults? Researchers will compare crisaborole 2% ointment to tacrolimus 0.1% ointment to see if crisaborole works as effective and is as well-tolerated. Participants will: * apply topical crisaborole 2% ointment or tacrolimus 0.1% oi

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age โ‰ฅ 6 years old. * Both male and female patients. * Localized facial vitiligo involving less than 50% of the facial surface area. * Stable vitiligo defined by fulfillment of both of the following criteria simultaneously at screening: * Vitiligo Disease Activity (VIDA) score โ‰ค 0. * Vitiligo Signs of Activity Score (VSAS) = 0. * Ability and willingness to comply with treatment and follow-up visits Exclusion Criteria: * Patients younger than 6 years. * Segmental vitiligo. * Vitiligo universalis. * Pregnancy \& breastfeeding. * History of transplantation procedure for vitiligo within the past 6 months. * History of hypersensitivity to the study medication. * History of any skin bleaching treatment for vitiligo or other dermatoses at any point. * Any contraindication to excimer light therapy e.g., history of skin cancer, photosensitivity disorders. * Current history of systemic therapy or phototherapy. * Any topical treatment (such as topical steroids, calcineurin inhibitors, vitamin D analogs, JAK inhibitors, PDE4i) requires a washout period of 2 weeks before screening visit and through the final safety follow-up visit. * Ultraviolet light exposure, including UVB/UVA/PUVA delivered by booth/excimer laser, or tanning bed exposure, requires a washout period of 8 weeks before screening and through the final safety follow-up visit.
๐Ÿ’Š

What it tests

  • Crisaborole 2% topical ointment
  • tacrolimus 0.1%
  • Excimer Light therapy
๐Ÿ“

Where

1 site
Faculty of Medicine, Cairo University
Cairo, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy