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๐Ÿ“ฐ Latest breakthroughs
๐Ÿ—บ๏ธ Disease Atlas ยท Cancer or benign tumor

cervical adenosquamous carcinoma

An uncommon carcinoma arising from the cervix. It is composed of malignant glandular epithelial cells and malignant squamous epithelial cells.

๐Ÿ”” Follow weekly
๐Ÿงฌ65genes / proteins with evidence
๐Ÿ’Š5drugs and clinical candidates
๐Ÿงช8recruiting trials worldwide
โœ…1phase 3
๐Ÿ“ˆ4phase 2
๐Ÿงฌ

Understand cervical adenosquamous carcinoma

Cancer ยท Cells that grow out of control
๐ŸŽ“ Learn more

What it is

An uncommon carcinoma arising from the cervix. It is composed of malignant glandular epithelial cells and malignant squamous epithelial cells.

From the Open Targets disease record โ†—

๐Ÿงฌ Cancer: Cancer is a group of diseases in which some of the body's cells grow and divide without control, and can spread to other parts of the body.

โ“ Why it happens

  • Changes (mutations) build up in the genes that tell a cell when to grow, divide and die.
  • Most of these changes happen during life: tobacco, too much sun, alcohol, some infections (such as HPV and hepatitis B and C), radiation, obesity and ageing all raise the risk.
  • Some people inherit a faulty gene that raises their risk, such as BRCA1 or BRCA2.

๐Ÿซ€ What it does to the body

  • Cancer cells form a lump (tumour) that can press on or invade nearby organs.
  • They can travel through the blood or lymph to start new tumours elsewhere (metastasis).
  • Blood cancers crowd out healthy blood cells in the bone marrow.

๐Ÿงฑ Why it is hard to cure

  • Every cancer is different, even between two people with the same type - and inside one tumour.
  • Cancer cells keep changing, so they can learn to resist a medicine that worked at first.
  • Cancer cells are the body's own cells, so killing them without harming healthy cells is hard.
  • Many cancers cause no symptoms until they have spread, and a new medicine often takes more than ten years to go from the lab to patients.

๐Ÿš€ What research is trying now

  • Targeted medicines against the exact gene change in a tumour (for example EGFR, ALK or KRAS).
  • Immunotherapy that helps the immune system recognise cancer, including CAR-T cell therapy.
  • Personalised cancer vaccines built from each tumour's mutations, now in late trials.
  • Blood tests that look for tumour DNA to find cancer earlier, and AI to read scans and slides.

General information about cancer, reviewed by people; it does not describe any one person. Below: the evidence for cervical adenosquamous carcinoma itself.

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AI briefing

Where the science on cervical adenosquamous carcinoma stands, from the evidence on this page

AI reads the targets, drugs, trials and papers below and writes where the science stands โ€” every claim cited. It is shared with everyone who opens cervical adenosquamous carcinoma.

๐ŸŽฏ

Top targets

Genes and proteins ranked by Open Targets evidence (0-1)
CRTC1 CREB regulated transcription coactivator 1PROTACantibody๐ŸงŠ AlphaFold structure โ†— 0.37
MAML2 mastermind like transcriptional coactivator 2๐ŸงŠ AlphaFold structure โ†— 0.37
SETD2 SET domain containing 2, histone lysine methyltransferasePROTACsmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
ERBB2 erb-b2 receptor tyrosine kinase 2PROTACantibodyothersmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
HRAS HRas proto-oncogene, GTPasePROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
PTEN phosphatase and tensin homologPROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
MTOR mechanistic target of rapamycin kinasePROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
FGFR2 fibroblast growth factor receptor 2PROTACantibodyothersmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
KRAS KRas proto-oncogene, GTPasePROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
DDX3X DEAD-box helicase 3 X-linkedPROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
FBXW7 F-box and WD repeat domain containing 7PROTACsmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphaPROTACantibodysmall molecule๐ŸงŠ AlphaFold structure โ†— 0.28
GNAS GNAS complex locus๐ŸงŠ AlphaFold structure โ†— 0.19
EP300 EP300 lysine acetyltransferasePROTACsmall molecule๐ŸงŠ AlphaFold structure โ†— 0.19
FGFR1 fibroblast growth factor receptor 1PROTACantibodyothersmall molecule๐ŸงŠ AlphaFold structure โ†— 0.19

Green labels: what the target is known to be druggable by. The score combines genetics, somatic mutations, drugs, expression and literature.

๐Ÿ’Š

Drugs and candidates

Every medicine linked to cervical adenosquamous carcinoma, by how far it has got
In phase 2 / 3 ยท 5
CisplatinPhase 3
CamrelizumabProgrammed cell death protein 1 antagonistPhase 2
CarboplatinPhase 2
PemetrexedThymidylate synthase inhibitor; Dihydrofolate reductase inhibitorPhase 2
SerplulimabProgrammed cell death protein 1 antagonistPhase 2
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy