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An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.
Lupus is a chronic (long-lasting) type of autoimmune disease. Autoimmune diseases happen when your immune system attacks healthy cells and tissues by mistake. This attack causes inflammation. It can also damage many parts of the body, including the joints, skin, kidneys, heart, lungs, and brain.
There are several types of lupus:
Systemic lupus erythematosus (SLE) is the most common type. It can be mild or severe and can affect many parts of the body.
From MedlinePlus: Lupus (US National Library of Medicine) ↗
🛡️ Autoimmune diseases: In autoimmune diseases the immune system, which should fight germs, attacks the body's own healthy tissue - the joints in rheumatoid arthritis, many organs in lupus, nerves in multiple sclerosis.
General information about autoimmune diseases, reviewed by people; it does not describe any one person. Below: the evidence for systemic lupus erythematosus itself.
AI reads the targets, drugs, trials and papers below and writes where the science stands — every claim cited. It is shared with everyone who opens systemic lupus erythematosus.
Green labels: what the target is known to be druggable by. The score combines genetics, somatic mutations, drugs, expression and literature.
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