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Hereditary nonpolyposis colon cancer: the latest breakthroughs

Everything that changed in the last year, from three public sources: phase 3 trials that posted their results, papers in the leading medical and cancer journals, and US drug labels that were updated. Refreshed every week.

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What changed

Written by AI from the evidence below, every point cited

AI reads the results, papers and label updates below and explains what changed and why it matters, citing each source. It is shared with everyone.

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Phase 3 results posted

The large trials that decide new standard treatments · ClinicalTrials.gov
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch RepairNCT02912559 · results posted 2026-04-14 · National Cancer Institute (NCI) · 712 people · tests Atezolizumab, Biospecimen Collection, Computed Tomography, Fluorouracil
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In the leading journals

NEJM, Lancet, Nature, JCO, Cancer Cell and more · PubMed
Anatomopathological Aspects and Clinical Correlation of Conjunctival Bleb Fibrosis Following Encapsulation of a Biodegradable Collagen Matr…Turk J Ophthalmol 2026 · PMID 42929100 Diagnostic flattening at the psychiatric-somatic interface: lessons from orofacial pain.Br J Psychiatry 2026 · PMID 42929099 Impact of age and frailty on the effect of a multimodal individualized long-term intervention after stroke: the last-long trial.J Rehabil Med 2026 · PMID 42929098 Human Development and the Architecture of Everyday Worry: Latent Worry Profiles in the World Risk Poll.Risk Anal 2026 · PMID 42929097 It is time for idiographic, network-informed clinical research for comorbid insomnia and depression.Br J Psychiatry 2026 · PMID 42929096 Polarity-Mediated β-Phase Reconstruction and Dual-Salt Synergy for Fast Li(+) Transport in Solid-State Li Metal Batteries.Small Methods 2026 · PMID 42929095 Scanless Centimeter-Scale Microstereolithography Enabled by Source-Plane Angular Conditioning.Small Methods 2026 · PMID 42929094 sandwrm: An R Package for Estimating Wright's Neighbourhood Size and Species-Level Genetic Diversity.Mol Ecol Resour 2026 · PMID 42929093 Genetic evidence linking gout to increased risk of epilepsy: A two-sample Mendelian randomization study.Adv Clin Exp Med 2026 · PMID 42929092 It takes a village to raise a child: how evolutionary anthropology can inform perinatal psychiatry.Br J Psychiatry 2026 · PMID 42929091 Ventilation inhomogeneity in Duchenne muscular dystrophy before the initiation of ventilatory support: Insights from electrical impedance t…Pulmonology 2026 · PMID 42929090 Eponymous Pupillary and Ocular Sensory Signs of Neurosyphilis: A Historical Review.Turk J Ophthalmol 2026 · PMID 42929089
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US drug labels updated

A label changes when a new use, dose or warning is approved · openFDA

No label updates found.

An update is not always a new approval — open the label to see what changed.

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