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An autosomal dominant hereditary syndrome caused by germline pathogenic POLE variants. It is characterized by the presence of colorectal polyps and colorectal cancer.
An autosomal dominant hereditary syndrome caused by germline pathogenic POLE variants. It is characterized by the presence of colorectal polyps and colorectal cancer.
From the Open Targets disease record ↗
🧬 Cancer: Cancer is a group of diseases in which some of the body's cells grow and divide without control, and can spread to other parts of the body.
General information about cancer, reviewed by people; it does not describe any one person. Below: the evidence for POLE-related polyposis and colorectal cancer syndrome itself.
AI reads the targets, drugs, trials and papers below and writes where the science stands — every claim cited. It is shared with everyone who opens POLE-related polyposis and colorectal cancer syndrome.
Green labels: what the target is known to be druggable by. The score combines genetics, somatic mutations, drugs, expression and literature.
No drugs recorded yet.
No recruiting trials found.
Search more trials →No papers found.
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