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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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28 recruiting trials

for ฮฒ -Thalassemia

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (ฮฒ)-Thalassemia NCT04143724Phase 226 sites๐Ÿ“ Los Angeles๐Ÿ“ New York๐Ÿ“ Guangzhou Celgene ยท Tests: ACE-536 Clinical Study of Super Transplantation in the Treatment of Severe ฮฒ-thalassemia NCT06734520NA2 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Guangzhou Women and Children's Medical Center ยท Tests: super-transplantation in 3 severe ฮฒ -thalassemia pediatric patients. Evaluating Safety and Efficacy of Lentiviral-transduced CD34+ HSCs in ฮ’-thalassaemia Patients. NCT06655662Phase 13 sites๐Ÿ“ Guangxi๐Ÿ“ Shenzhen๐Ÿ“ Shenzhen Shenzhen Hemogen ยท Tests: ฮฒ-globin restored autologous hematopoietic stem cells Long-term Follow-up Study of BHC001 for TDT NCT06314529n/a2 sites๐Ÿ“ Nanning๐Ÿ“ Changsha Bioray Laboratories ยท Tests: Assessments A Study of Immune Suppression Treatment for People With Sickle Cell Disease or ฮฒ-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) NCT05736419Phase 26 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Fludarabine, Cyclophosphamide, Tacrolimus, Mycophenolate Mofetil, Rabbit ATG A Trial Testing SP-420 in Subjects With Transfusion-dependent ฮฒ-thalassemia or Low-risk Myelodysplastic Syndromes NCT05693909Phase 21 site๐Ÿ“ Copenhagen Pharmacosmos A/S ยท Tests: SP-420 A Long-term Follow-up Study in Participants Who Received CS-101 NCT06479616NA1 site๐Ÿ“ Shanghai Children's Hospital of Fudan University ยท Tests: CS-101 A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or ฮฒ-thalassemia NCT06073860n/a2 sites๐Ÿ“ Seoul๐Ÿ“ Seoul Bristol-Myers Squibb ยท Tests: Luspatercept A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent ฮฒ-Thalassemia [TDT] NCT05762510EARLY Phase 11 site๐Ÿ“ Nanning First Affiliated Hospital of Guangxi Medical University ยท Tests: GMCN-508B (LentiRed) Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent ฮฒ-Thalassemia and Severe Sickle Cell Disease NCT05477563Phase 36 sites๐Ÿ“ New York๐Ÿ“ Charlotte๐Ÿ“ Nashville Vertex Pharmaceuticals Incorporated ยท Tests: CTX001 Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-thalassemia NCT05773729NA1 site๐Ÿ“ Shanghai Shanghai BDgene Co., Ltd. ยท Tests: BD211 Safety and Efficacy of the Lentiviral Vector in Gene Therapy of Beta-thalassemia Patients NCT06219239NA1 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: KL003 cell injection Drug Product A Multiple Ascending Dose Study of 9MW3011 in Patients With Non-transfusion-dependent ฮฒ-thalassemia NCT06772766Phase 12 sites๐Ÿ“ Nanning๐Ÿ“ Haikou Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW3011, 9MW3011 placebo Combination Therapy With Danazol, Prednisolone, and Thalidomide for Thalidomide-Refractory Transfusion-Dependent ฮฒ-Thalassemia NCT07884773Phase 31 site๐Ÿ“ Peshawar Khyber Medical University Peshawar ยท Tests: Thalidomide, Danazol, Prednisolone Evaluating the Clinical Efficacy and Safety of Luspatercept Combined With Thalidomide in the Treatment of ฮฒ-TDT Patients NCT07338344Phase 28 sites๐Ÿ“ Shenzhen๐Ÿ“ Baise City๐Ÿ“ Baise City Rongrong Liu ยท Tests: Luspatercept combined with low-dose thalidomide, Luspatercept plus placebo Safety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent ฮฒ-thalassemia NCT05776173NA1 site๐Ÿ“ Shanghai Shanghai BDgene Co., Ltd. ยท Tests: BD211 A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (ฮฑ- or ฮฒ-TDT) NCT07506863Phase 34 sites๐Ÿ“ Atlanta๐Ÿ“ New York๐Ÿ“ Philadelphia Agios Pharmaceuticals, Inc. ยท Tests: Mitapivat Matched Placebo, Mitapivat A Study of Participants with ฮ’-Thalassemia Treated with Betibeglogene Autotemcel NCT06271512n/a6 sites๐Ÿ“ Oakland๐Ÿ“ Palo Alto๐Ÿ“ Minneapolis Genetix Biotherapeutics Inc. ยท Tests: No Intervention ฮ’-Thalassemia Treatment with KL003 Cell Injection NCT06280378Phase 1, Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Tianjin Kanglin Biotechnology (Hangzhou) Co., Ltd. ยท Tests: KL003 Cell Injection Drug Product Long-term Follow-up Study of BRL-101 for TDT NCT06298630n/a7 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Shenzhen Bioray Laboratories ยท Tests: Assessments A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With ฮฑ- or ฮฒ-Non-Transfusion-Dependent Thalassemia NCT07517133Phase 35 sites๐Ÿ“ Palo Alto๐Ÿ“ Atlanta๐Ÿ“ New York Agios Pharmaceuticals, Inc. ยท Tests: Mitapivat, Placebo Matching Mitapivat Safety and Efficacy Evaluation of ฮฒ-globin Restored Autologous Hematopoietic Stem Cells in ฮฒ-thalassemia Major Patients NCT05745532EARLY Phase 11 site๐Ÿ“ Shenzhen Shenzhen Hemogen ยท Tests: ฮฒ-globin restored autologous hematopoietic stem cells the Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent ฮฒ-Thalassemia NCT05864170EARLY Phase 11 site๐Ÿ“ Shenzhen Shenzhen Hemogen ยท Tests: ฮฒ-globin restored autologous hematopoietic stem cells A Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middle East NCT07215975n/a13 sites๐Ÿ“ Al Jahra๐Ÿ“ Andalusia๐Ÿ“ Kuwait City Bristol-Myers Squibb ยท Tests: Luspatercept Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe ฮฒ-Hemoglobinopathies NCT06647979Phase 11 site๐Ÿ“ Boston Daniel Bauer ยท Tests: autologous bone marrow derived CD34+ HSPCs electroporated with BCL11A enhancer targeting Cas9 ribonucleoprotein, Sequenโ€ฆ Evaluation of Physiological and Psychological Factors Involved in Exercise Intolerance in Patients With ฮฒ-TTD NCT07207577NA1 site๐Ÿ“ Chambรฉry Centre Hospitalier Metropole Savoie ยท Tests: Maximal incremental exercise test A Study of Safety and Efficiency of AND017 in Patients With ฮฒ-thalassemia NCT06302491Phase 25 sites๐Ÿ“ Guangzhou๐Ÿ“ Maoming๐Ÿ“ Liuzhou Kind Pharmaceuticals LLC ยท Tests: AND017 capsules, AND017 Placebo A Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating ฮฒ-thalassemia Major NCT06465550Phase 13 sites๐Ÿ“ Guangzhou๐Ÿ“ Nanning๐Ÿ“ Shanghai Shanghai BDgene Co., Ltd. ยท Tests: BD211
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