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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Adult Glioblastoma

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma NCT07452458Phase 354 sites📍 Irvine📍 Los Angeles📍 Orange NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Questionnaire Administration, Radiation Therapy hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) NCT05052957Phase 21 site📍 Cleveland Leland Metheny · Tests: P140K-MGMT, O6-benzylguanine, Photon Based Radiotherapy, temozolomide, Filgrastim Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature NCT06894225Phase 21 site📍 Singapore National Neuroscience Institute · Tests: ACT001 Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma NCT06991101Phase 22 sites📍 Miami📍 New York Baptist Health South Florida · Tests: Ruxolitinib, Temozolomide, Radiation Therapy Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM). NCT06297512Phase 21 site📍 Florence Iacopo Sardi · Tests: Radiotherapy, Temozolomide, Doxorubicin Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study NCT06954636n/a2 sites📍 Essen📍 Münster Sied Kebir · Tests: olfactory testing (threshold and identification test) Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy NCT07179328Phase 11 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Focused Ultrasound Next Generation Dome Helmet, Definity® Vial for (Perflutren Lipid Microsphere) Injectable Suspension Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites📍 Phoenix📍 Little Rock📍 Castro Valley GT Medical Technologies, Inc. · Tests: GammaTile Key Longitudinal Associations With Risk and Glioblastoma Outcomes NCT06625684n/a1 site📍 Durham Duke University The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) NCT06146738n/a8 sites📍 San Francisco📍 Boston📍 Leuven Jasper Gerritsen · Tests: Palliative Care, Tumor biopsy, Tumor resection Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors NCT05283330Phase 18 sites📍 Chicago📍 Iowa City📍 Lexington Orano Med Theranostics, SAS · Tests: ²¹²Pb-DOTAM-GRPR1 ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors NCT07523529Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: Autologous dual-target CAR-T cells selected from the predefined target library., Fludarabine, Cyclophosphamide Hypofractionated Radiotherapy NCT06740955NA1 site📍 Changchun The First Hospital of Jilin University · Tests: hypofractionated postoperative radiotherapy, Conventionally fractionated postoperative radiotherapy A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites📍 Washington D.C.📍 Gainesville University of Florida · Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP li… D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients NCT05734560Phase 1, Phase 21 site📍 Durham Darell Bigner · Tests: D2C7-IT, 2141-V11 Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma NCT07551336Phase 11 site📍 Shenzhen Beijing Biotech · Tests: Dual-target CAR-NK cells, Cyclophosphamide, Intracranial catheter/reservoir for locoregional delivery, Fludarabine Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma NCT05954858NA1 site📍 New York Northwell Health · Tests: Tissue autograft of pedicled temporoparietal fascial (TPF) or pericranial flap to bypass the blood brain barrier (BBB) A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. NCT07134842Phase 11 site📍 London University College, London · Tests: Ipilimumab (3 mg/kg) B7-H3 Chimeric Antigen Receptor T Cells (B7-H3CART) in Recurrent Glioblastoma Multiforme NCT05474378Phase 11 site📍 Palo Alto Stanford University · Tests: B7-H3CART Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma NCT07100730Phase 39 sites📍 Gold Coast📍 Melbourne📍 Perth Telix Pharmaceuticals (Innovations) Pty Limited · Tests: TLX-101-Tx + Lomustine, TLX101-Tx Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant NCT05843253Phase 220 sites📍 Aurora📍 Washington D.C.📍 Chicago Nationwide Children's Hospital · Tests: Ribociclib, Everolimus, Temozolomide (TMZ) The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling NCT06717295n/a4 sites📍 Rosario📍 Lagos📍 Cambridge Javier Toledo · Tests: DiNanoQ: A multi-cancer early detection (MCED) blood test, DiNanoTrack: Therapeutic Response Monitoring Blood Test The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma NCT06273176n/a8 sites📍 San Francisco📍 Boston📍 Leuven Erasmus Medical Center · Tests: Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia witho… TTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0) NCT07668869NA1 site📍 Bydgoszcz Prof. Franciszek Lukaszczyk Memorial Oncology Center · Tests: Tumor Treating Fields (TTFields), FET-PET-Guided Stereotactic Radiosurgery DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) NCT06805305Phase 218 sites📍 Gilbert📍 Duarte📍 Newport Beach Diakonos Oncology Corporation · Tests: DOC1021, Tumor resection, Temodar (Temozolomide), SOC cranial radiation A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma NCT07464925Phase 13 sites📍 Tampa📍 Chicago📍 New York Tetragon Biosciences Ltd · Tests: GLIX1 Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma NCT05083754Phase 11 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Retifanlimab, Temozolomide, Radiation Therapy The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) NCT06118723n/a8 sites📍 San Francisco📍 Boston📍 Leuven Jasper Gerritsen · Tests: Supramaximal resection, Maximal safe resection Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors NCT07411690n/a1 site📍 Warsaw Medical University of Warsaw
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