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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Colorectal Cancer

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors NCT04557449Phase 1, Phase 239 sites๐Ÿ“ Los Angeles๐Ÿ“ New Haven๐Ÿ“ New Haven Pfizer ยท Tests: PF-07220060, Letrozole, Fulvestrant, Midazolam, Enzalutamide DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies NCT04678648Phase 13 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ Nashville RasCal Therapeutics, Inc. ยท Tests: RSC-1255 Dose Escalation, RSC-1255 Dose Expansion Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagiโ€ฆ A Clinical Study of SHR-A1811 in Combination With Chemotherapy and Bevacizumab Versus Standard Therapy as First-Line Treatment for Advanced Colorectal Cancer NCT07676162Phase 31 site๐Ÿ“ Beijing Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A1811, Oxaliplatin, Levo-leucovorin, Fluorouracil and Bevacizumab, Oxaliplatin, Levo-leucovorin, Fluorouracil and Bโ€ฆ Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites๐Ÿ“ Fairway๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Metarrestin CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Stanford BioEclipse Therapeutics ยท Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma NCT05752136Phase 31 site๐Ÿ“ Hangzhou Sir Run Run Shaw Hospital ยท Tests: Envafolimab TT-702 in Patients With Advanced Solid Tumours. NCT05272709Phase 1, Phase 23 sites๐Ÿ“ London๐Ÿ“ Manchester๐Ÿ“ Southampton Cancer Research UK ยท Tests: TT-702, Anti-PD-1 and PD-L1 agent Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer NCT06521866Phase 210 sites๐Ÿ“ Fuzhou๐Ÿ“ Xiamen๐Ÿ“ Lanzhou Fudan University ยท Tests: Serplulimab, Chemotherapy, SABR, Targeted therapy KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors NCT06026410Phase 138 sites๐Ÿ“ Phoenix๐Ÿ“ Tucson๐Ÿ“ Los Angeles Kura Oncology, Inc. ยท Tests: Darlifarnib, Cabozantinib, Adagrasib A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors NCT07318805Phase 113 sites๐Ÿ“ Duarte๐Ÿ“ Grand Rapids๐Ÿ“ Long Island City Pfizer ยท Tests: PF-08032562, Fulvestrant, Cetuximab, Fluorouracil, Oxaliplatin Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer NCT06530303Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Atlanta Amgen ยท Tests: AMG 410, Pembrolizumab, Panitumumab Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site๐Ÿ“ Beijing Seventh Medical Center of PLA General Hospital ยท Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy NCT05965531Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Trifluridine/Tipiracil, intensity-modulated radiotherapy Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer NCT06613165n/a1 site๐Ÿ“ Xi'an Xijing Hospital Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine As Conversion Therapy of Locally Advanced Colorectal Cancer NCT06405139Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Nanoliposomal Irinotecan, Oxaliplatin plus Capecitabine A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites๐Ÿ“ Vijayawada๐Ÿ“ Visakhapatnam๐Ÿ“ Chandigarh Aurigene Discovery Technologies Limited ยท Tests: AUR107 The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer NCT07204574Phase 1, Phase 21 site๐Ÿ“ Taoyuan Chang Gung Memorial Hospital ยท Tests: HCB101, Bevacizumab, Cetuximab (Erbitux), FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan), FOLFOX (Oxaliplatin/Leโ€ฆ A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors NCT07300150Phase 19 sites๐Ÿ“ Boston๐Ÿ“ San Antonio๐Ÿ“ San Antonio PAQ Therapeutics, Inc. ยท Tests: PT0511, Cetuximab The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial. NCT06477991n/a1 site๐Ÿ“ Kunming Yunnan Cancer Hospital ยท Tests: Tireilizumab๏ผˆPD-1 inhibitor๏ผ‰ TQB2922 and TAS-102 Tablets for Injection With or Without Bevacizumab in Chemotherapy-failed RAS/BRAF Wild-type Advanced Colorectal Cancer NCT07044908Phase 1, Phase 227 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Chongqing Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharโ€ฆ ยท Tests: TQB2922 injection ยฑ TAS-102 tablets, TQB2922 injection+TAS-102 tablets ยฑ Bevacizumab Watch and Wait as Treatment for Patients With Rectal Cancer NCT03125343NA2 sites๐Ÿ“ Gothenburg๐Ÿ“ Stockholm Sahlgrenska University Hospital ยท Tests: endoscopy, Surgery, MRI Irinotecan Hydrochloride Liposome Injection (โ…ก) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetuximab in First-line Treatment of BRAFV600E Mutated Advanced Colorectal Cancer NCT06603376Phase 21 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: FOLFIRI + Vemurafenib + Cetuximab, FOLFIRI ยฑ Bevacizumab CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors NCT07749586Phase 1, Phase 24 sites๐Ÿ“ New York๐Ÿ“ Huntersville๐Ÿ“ San Antonio Arvinas Inc. ยท Tests: ARV-6723, Pembrolizumab, SOC Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors NCT04165772Phase 210 sites๐Ÿ“ Hartford๐Ÿ“ Miami๐Ÿ“ Basking Ridge Memorial Sloan Kettering Cancer Center ยท Tests: TSR-042 or Dostarlimab, capecitabine or 5-FU, Intensity Modulated Radiation Therapy (IMRT)
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