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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Colorectal Carcinoma

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors NCT04557449Phase 1, Phase 239 sites๐Ÿ“ Los Angeles๐Ÿ“ New Haven๐Ÿ“ New Haven Pfizer ยท Tests: PF-07220060, Letrozole, Fulvestrant, Midazolam, Enzalutamide DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagiโ€ฆ A Clinical Study of SHR-A1811 in Combination With Chemotherapy and Bevacizumab Versus Standard Therapy as First-Line Treatment for Advanced Colorectal Cancer NCT07676162Phase 31 site๐Ÿ“ Beijing Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A1811, Oxaliplatin, Levo-leucovorin, Fluorouracil and Bevacizumab, Oxaliplatin, Levo-leucovorin, Fluorouracil and Bโ€ฆ CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Stanford BioEclipse Therapeutics ยท Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide TT-702 in Patients With Advanced Solid Tumours. NCT05272709Phase 1, Phase 23 sites๐Ÿ“ London๐Ÿ“ Manchester๐Ÿ“ Southampton Cancer Research UK ยท Tests: TT-702, Anti-PD-1 and PD-L1 agent Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer NCT06521866Phase 210 sites๐Ÿ“ Fuzhou๐Ÿ“ Xiamen๐Ÿ“ Lanzhou Fudan University ยท Tests: Serplulimab, Chemotherapy, SABR, Targeted therapy KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors NCT06026410Phase 138 sites๐Ÿ“ Phoenix๐Ÿ“ Tucson๐Ÿ“ Los Angeles Kura Oncology, Inc. ยท Tests: Darlifarnib, Cabozantinib, Adagrasib A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors NCT07318805Phase 113 sites๐Ÿ“ Duarte๐Ÿ“ Grand Rapids๐Ÿ“ Long Island City Pfizer ยท Tests: PF-08032562, Fulvestrant, Cetuximab, Fluorouracil, Oxaliplatin Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer NCT06530303Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors NCT07094113Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Atlanta Amgen ยท Tests: AMG 410, Pembrolizumab, Panitumumab Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer NCT06613165n/a1 site๐Ÿ“ Xi'an Xijing Hospital Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine As Conversion Therapy of Locally Advanced Colorectal Cancer NCT06405139Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Nanoliposomal Irinotecan, Oxaliplatin plus Capecitabine A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites๐Ÿ“ Vijayawada๐Ÿ“ Visakhapatnam๐Ÿ“ Chandigarh Aurigene Discovery Technologies Limited ยท Tests: AUR107 The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer NCT07204574Phase 1, Phase 21 site๐Ÿ“ Taoyuan Chang Gung Memorial Hospital ยท Tests: HCB101, Bevacizumab, Cetuximab (Erbitux), FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan), FOLFOX (Oxaliplatin/Leโ€ฆ A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors NCT07300150Phase 19 sites๐Ÿ“ Boston๐Ÿ“ San Antonio๐Ÿ“ San Antonio PAQ Therapeutics, Inc. ยท Tests: PT0511, Cetuximab The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial. NCT06477991n/a1 site๐Ÿ“ Kunming Yunnan Cancer Hospital ยท Tests: Tireilizumab๏ผˆPD-1 inhibitor๏ผ‰ TQB2922 and TAS-102 Tablets for Injection With or Without Bevacizumab in Chemotherapy-failed RAS/BRAF Wild-type Advanced Colorectal Cancer NCT07044908Phase 1, Phase 227 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Chongqing Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharโ€ฆ ยท Tests: TQB2922 injection ยฑ TAS-102 tablets, TQB2922 injection+TAS-102 tablets ยฑ Bevacizumab Irinotecan Hydrochloride Liposome Injection (โ…ก) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetuximab in First-line Treatment of BRAFV600E Mutated Advanced Colorectal Cancer NCT06603376Phase 21 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: FOLFIRI + Vemurafenib + Cetuximab, FOLFIRI ยฑ Bevacizumab CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors NCT07749586Phase 1, Phase 24 sites๐Ÿ“ New York๐Ÿ“ Huntersville๐Ÿ“ San Antonio Arvinas Inc. ยท Tests: ARV-6723, Pembrolizumab, SOC Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib A First in Human Study of PLT012 in Participants With Solid Tumor Cancers NCT07337525Phase 14 sites๐Ÿ“ Los Angeles๐Ÿ“ Dallas๐Ÿ“ Houston Pilatus Biosciences Inc ยท Tests: PLT012 FL-261 Imaging for Cancer Diagnosis and Staging NCT07510321n/a1 site๐Ÿ“ Wuhan Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: [68Ga]Ga-FL-261 PET Imaging / [111In]In-FL-261 SPECT Imaging TL938 and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer NCT06589830Phase 21 site๐Ÿ“ Beijing Suzhou Teligene Ltd. ยท Tests: TL938 Capsules, Trastuzumab A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors NCT05740956Phase 11 site๐Ÿ“ Beijing Jiangsu Hansoh Pharmaceutical Co., Ltd. ยท Tests: HS-10502 Study of MT-302 in Adults With Advanced or Metastatic Epithelial Tumors NCT05969041Phase 16 sites๐Ÿ“ Darlinghurst๐Ÿ“ Randwick๐Ÿ“ Westmead Myeloid Therapeutics ยท Tests: MT-302 (A) A Study of HDM2017 Combination Therapy in Advanced Colorectal Cancer NCT07805551Phase 1, Phase 21 site๐Ÿ“ Beijing Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. ยท Tests: HDM2017, Bevacizumab, Oxaliplatin, Fluorouracil, Capecitabine Advanced Therapies for Liver Metastases NCT04622423n/a1 site๐Ÿ“ Milan IRCCS San Raffaele
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