๐ŸŒ EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

๐Ÿงช

Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

๐ŸŽฏ Match trials to me

30 recruiting trials

for Advanced Malignancy

A Phase I Study of ABSK211 in Participants With Advanced Solid Tumors With KRAS Alteration NCT07718165Phase 11 site๐Ÿ“ Shanghai Abbisko Therapeutics Co, Ltd ยท Tests: ABSK211 Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma NCT06342167Phase 210 sites๐Ÿ“ Beijing๐Ÿ“ Fujian๐Ÿ“ Handan Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Radiotherapy, Programmed Cell Death Protein 1 Inhibitor, Immunonutrition support A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors NCT07414836Phase 118 sites๐Ÿ“ Boston๐Ÿ“ St Louis๐Ÿ“ Hackensack BeOne Medicines ยท Tests: BG-C0979, Tislelizumab A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer. NCT06481592Phase 212 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Orlando Iovance Biotherapeutics, Inc. ยท Tests: Lifileucel ChemoINTEL Assay Algorithm Development Study: In-Vitro Cytotoxic Drug Induced Apoptosis Correlation with Patient Clinical Response to Administered Chemotherapy in Patients NCT06844136n/a1 site๐Ÿ“ Liverpool Pierian Biosciences ยท Tests: No intervention Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment NCT05661461Phase 12 sites๐Ÿ“ San Antonio๐Ÿ“ West Valley City Aadi Bioscience, Inc. ยท Tests: nab-sirolimus A Study to Assess the Safety and Efficacy of LB1410 in Participants With Advanced Solid Tumor or Lymphoma๏ผˆKeyplus-001๏ผ‰ NCT05357651Phase 11 site๐Ÿ“ Shanghai L & L Bio Co., Ltd., Ningbo, China ยท Tests: LB1410 Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor NCT05933395Phase 21 site๐Ÿ“ Lebanon Dartmouth-Hitchcock Medical Center ยท Tests: Fulvestrant, Neratinib, Alpelisib, Everolimus, Abemaciclib Elacestrant in Patients With ER+ HER2- ESR1-mutated Locally Advanced or Metastatic Breast Cancer NCT07563595n/a3 sites๐Ÿ“ Freiburg im Breisgau๐Ÿ“ Paderborn๐Ÿ“ Ravensburg iOMEDICO AG ยท Tests: Elacestrant, Standard of care (Investigator Choice) Yunzhi Essence to Improve the Quality of Life of Patients With Advanced Stage of Cancer NCT05754801Phase 21 site๐Ÿ“ Hong Kong Chinese University of Hong Kong ยท Tests: Yunzhi Essence, Placebo A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors NCT06349811Phase 11 site๐Ÿ“ Beijing Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-M05D1 An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting NCT06749886Phase 21 site๐Ÿ“ Shanghai Shanghai Pulmonary Hospital, Shanghai, China ยท Tests: Denosumab, tislelizumab, Docetaxel Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC NCT06876753n/a2 sites๐Ÿ“ Nanjing๐Ÿ“ Nanjing Zhongda Hospital An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors NCT07222267Phase 132 sites๐Ÿ“ Birmingham๐Ÿ“ New Haven๐Ÿ“ St Louis BeOne Medicines ยท Tests: BG-75202, CDK4 Inhibitor, Estrogen Receptor Antagonist, Aromatase Inhibitor A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations NCT06947811Phase 1, Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Almonertinib, Palbociclib Laparoscopic Gastrectomy With D2 Lymphadenectomy Combined With Hyperthermic Intraperitoneal Chemotherapy (HIPEC) or Not NCT05871099Phase 31 site๐Ÿ“ Qingdao The Affiliated Hospital of Qingdao University ยท Tests: Hyperthermic Intraperitoneal Chemotherapy (HIPEC) MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors NCT06912152Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: MT027 CAR-T cells A Real World Study of Ensartinib in Advanced ALK-positive NSCLC NCT05498064n/a1 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Ensartinib Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation NCT05010109NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: 6 Minute Walk Functional Test, Biospecimen Collection, Computed Tomography, Echocardiography, Exercise Cardiac Stress Tโ€ฆ Neoadjuvant Iparomlimab and Tuvonralimab Plus Chemotherapy-eclipse for Locally Advanced Cervical Cancer (NICE-CC) NCT07055399Phase 21 site๐Ÿ“ Fuzhou Fujian Cancer Hospital ยท Tests: neoadjuvant chemo-immunotherapy: Iparomlimab and tuvonralimab plus cisplatin,nab-paclitaxel for 1 cycle and Iparomlimabโ€ฆ FOLFOX Combined With Durvalumab (MEDI4736), Bevacizumab, and Stereotactic Body Radiotherapy in Sequential Treatment of Potentially Resectable Locally Advanced Hepatocellular Carcinoma NCT07012798Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Durvalumab, Bevacizumab, HAIC of FOLFOX ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR) NCT06415487Phase 19 sites๐Ÿ“ San Diego๐Ÿ“ Denver๐Ÿ“ Nashville Acepodia Biotech, Inc. ยท Tests: Cyclophosphamide, Fludarabine, ACE2016, Pembrolizumab Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC NCT06162221Phase 1, Phase 298 sites๐Ÿ“ Gilbert๐Ÿ“ Duarte๐Ÿ“ Irvine Revolution Medicines, Inc. ยท Tests: RMC-6291, RMC-6236, Pembrolizumab, Cisplatin, Carboplatin Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors NCT04557449Phase 1, Phase 239 sites๐Ÿ“ Los Angeles๐Ÿ“ New Haven๐Ÿ“ New Haven Pfizer ยท Tests: PF-07220060, Letrozole, Fulvestrant, Midazolam, Enzalutamide A Phase I Study of HS-20108 in Participants With Advanced Solid Tumors NCT06936735Phase 11 site๐Ÿ“ Shanghai Hansoh BioMedical R&D Company ยท Tests: HS-20108 Monotherapy Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of BAT8008 for Injection NCT05620017Phase 12 sites๐Ÿ“ Chongqing๐Ÿ“ Hangzhou Bio-Thera Solutions ยท Tests: BAT8008 for Injection Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors NCT06835387Phase 27 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fort Wayne Tiago Biachi de Castria ยท Tests: Nanoliposomal irinotecan, Oxaliplatin, 5 fluorouracil, Leucovorin Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer. NCT05378204NA25 sites๐Ÿ“ Bordeaux๐Ÿ“ Caen๐Ÿ“ Clermont-Ferrand Institut Claudius Regaud ยท Tests: Main study:, Sub-study: DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010) NCT07785609Phase 24 sites๐Ÿ“ San Antonio๐Ÿ“ Hong Kong๐Ÿ“ Bellinzona Merck Sharp & Dohme LLC ยท Tests: MK-2010, Sacituzumab tirumotecan, Histamine H1 Receptor Antagonist, Histamine H2 Receptor Antagonist, Acetaminophen (orโ€ฆ
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy