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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced Malignant Solid Tumors

MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors NCT06912152Phase 11 site📍 Hangzhou Zhejiang University · Tests: MT027 CAR-T cells A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010) NCT07785609Phase 24 sites📍 San Antonio📍 Hong Kong📍 Bellinzona Merck Sharp & Dohme LLC · Tests: MK-2010, Sacituzumab tirumotecan, Histamine H1 Receptor Antagonist, Histamine H2 Receptor Antagonist, Acetaminophen (or… A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies NCT04678648Phase 13 sites📍 Los Angeles📍 Denver📍 Nashville RasCal Therapeutics, Inc. · Tests: RSC-1255 Dose Escalation, RSC-1255 Dose Expansion Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers NCT06606990Phase 11 site📍 Bethesda National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors NCT07387068Phase 112 sites📍 New Haven📍 Grand Rapids📍 Lake Success Genmab · Tests: GEN1079 Phase 1 Study of MST-168 in Participants With Advanced Solid Malignant Tumors NCT07644650Phase 11 site📍 Shanghai Mabsoft Therapeutics (Shanghai) Co., Ltd. · Tests: MST-168 Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites📍 Fairway📍 Bethesda National Cancer Institute (NCI) · Tests: Metarrestin JSKN022 in Subjects With Advanced Malignant Solid Tumors NCT07292402Phase 11 site📍 Guangzhou Jiangsu Alphamab Biopharmaceuticals Co., Ltd · Tests: JSKN022 CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites📍 Scottsdale📍 La Jolla📍 Stanford BioEclipse Therapeutics · Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide Study of MHB088C for Patients With Advanced Solid Malignant Tumors NCT07102004Phase 1, Phase 21 site📍 Beijing Qilu Pharmaceutical Co., Ltd. · Tests: MHB088C for Injection Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial NCT06470971Phase 21 site📍 Columbus Yuanquan Yang · Tests: Anti-PD-L1 Monoclonal Antibody, Anti-PD1 Monoclonal Antibody, Biopsy, Biospecimen Collection, Bone Scan Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors NCT04879121Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Larotrectinib Sulfate Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors NCT05141474EARLY Phase 11 site📍 Barcelona Vall d'Hebron Institute of Oncology · Tests: NEXTGEN-TIL, Non-myeloablative Lymphodepletion (NMA-LD) Regimen, Interleukin-2 Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors NCT07583654Phase 11 site📍 Chengdu West China Hospital · Tests: CP-IL22BP mRNA intratumorally injection Using Neoantigen Peptide Vaccine/neoantigen-based DC to Treat Advanced Malignant Solid Tumors NCT05749627NA1 site📍 Nanchang The First Affiliated Hospital of Nanchang University · Tests: Neoantigen peptide vaccine, Neoantigen-based DC immune preparation Anti-HER2 CAR-T Cell Injection in Patients With HER2-positive Advanced Malignant Solid Tumors NCT06658951NA1 site📍 Zhengzhou UTC Therapeutics Inc. · Tests: Anti-HER2 CAR-T cells Atamparib in Patients With Advanced Solid Tumors NCT07374419Phase 1, Phase 21 site📍 Shanghai Nerviano Medical Sciences (Shanghai) Ltd. · Tests: atamparib escalation levels, atamparib RP2D A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites📍 Vijayawada📍 Visakhapatnam📍 Chandigarh Aurigene Discovery Technologies Limited · Tests: AUR107 Study of LM-299 in Subjects Advanced Malignant Tumors NCT06650566Phase 1, Phase 26 sites📍 Perth📍 Xinxiang📍 Liaocheng LaNova Medicines Limited · Tests: LM-299 Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Talazoparib and Palbociclib, Axitinib, or Crizotinib for the Treatment of Advanced or Metastatic Solid Tumors, TalaCom Trial NCT04693468Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Axitinib, Crizotinib, Palbociclib Isethionate, Talazoparib Tosylate CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites📍 Denver📍 Chicago📍 Grand Rapids Context Therapeutics Inc. · Tests: CT-95 IBI343 in Combination Therapy for Advanced Malignant Solid Tumors NCT07483554Phase 21 site📍 Hangzhou Innovent Biologics (Suzhou) Co. Ltd. · Tests: IBI343,Gemcitabine, Albumin-bound Paclitaxel Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib A First in Human Study of PLT012 in Participants With Solid Tumor Cancers NCT07337525Phase 14 sites📍 Los Angeles📍 Dallas📍 Houston Pilatus Biosciences Inc · Tests: PLT012 FL-261 Imaging for Cancer Diagnosis and Staging NCT07510321n/a1 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: [68Ga]Ga-FL-261 PET Imaging / [111In]In-FL-261 SPECT Imaging YH02 Injection for Intra-tumor Injection Therapy in Advanced Solid Tumors With Unresponsive or Failure-Treated Cases NCT07697937Phase 21 site📍 Tianjin Tianjin First Central Hospital · Tests: YH-02 Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors NCT06320405Phase 1, Phase 21 site📍 Portland OHSU Knight Cancer Institute · Tests: Axatilimab, Biopsy, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma NCT07189195Phase 11 site📍 Sacramento University of California, Davis · Tests: TR-002
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