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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Advanced or Metastatic Melanoma

Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma NCT07627698Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-DTKN-401 allogeneic dual-target CSPG4/GD2 CAR-NK cells, Fludarabine, Cyclophosphamide To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma NCT06204991Phase 12 sites๐Ÿ“ Herlev๐Ÿ“ Herlev Inge Marie Svane ยท Tests: ADP-TILIL7, Cyclophosphamide, Fludarabine Phosphate, Proleukin Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naรฏve, Cutaneous Melanoma Study NCT07050940NA5 sites๐Ÿ“ Bari๐Ÿ“ Torino๐Ÿ“ Bari Azienda Ospedaliera di Perugia ยท Tests: Postbiotic, AntiPD1 A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5) NCT07492680Phase 258 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Bristol-Myers Squibb ยท Tests: BMS-986504, Daraxonrasib, Nivolumab + Relatlimab FDC, Temozolomide, Pumitamig Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib A Study of LN-144 or LN-145 in People With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma NCT05607095Phase 12 sites๐Ÿ“ Harrison๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: Lifileucel (LN-144/LN-145) Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites๐Ÿ“ Scottsdale๐Ÿ“ Bethesda๐Ÿ“ Columbus Novartis Pharmaceuticals ยท Tests: dabrafenib, trametinib Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. NCT05727904Phase 382 sites๐Ÿ“ Birmingham๐Ÿ“ Duarte๐Ÿ“ Los Angeles Iovance Biotherapeutics, Inc. ยท Tests: Lifileucel plus Pembrolizumab, Pembrolizumab with Optional Crossover Period Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases NCT05909618Phase 21 site๐Ÿ“ Ramat Gan Sheba Medical Center ยท Tests: Crizanlizumab-Tmca 10 MG/1 ML Intravenous Solution [ADAKVEO], Nivolumab 10 MG/1 ML Intravenous Solution [OPDIVO] Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivoยฎ in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma NCT07221734Phase 319 sites๐Ÿ“ Funchal๐Ÿ“ Chernivtsi๐Ÿ“ Ivano-Frankivsk mAbxience Research S.L. ยท Tests: MB11 (Proposed Nivolumab Biosimilar), EU-Opdivoยฎ, US- sourced Opdivoยฎ Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma NCT06295159Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Nivolumab, Nivolumab + Relatlimab, Ipilimumab A Study to Evaluate the Efficacy and Safety of IBI363 Monotherapy Compared to Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal or Acral Melanoma Who Had Not Previously Received Systemic Therapy NCT06797297Phase 231 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI363, Pembrolizumab Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors NCT05629546Phase 11 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: Cytokine-induced memory-like natural killer cells, Relatilmab, Nivolumab EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ยฑ Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: EBNK-001 + IL-15 + Pembrolizumab A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3 NCT06887348n/a2 sites๐Ÿ“ La Jolla๐Ÿ“ Southport Replimune, Inc. ยท Tests: Observational study with no interventions A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma NCT07223411n/a1 site๐Ÿ“ Pittsburgh John Kirkwood ยท Tests: Fianlimab + Cemiplimab, Relatlimab + Nivolumab Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC NCT06332755Phase 11 site๐Ÿ“ Fairfax LG Chem ยท Tests: Phase 1a: LB-LR1109, Phase 1b: LB-LR1109 and Atezolizumab A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit NCT06805825Phase 15 sites๐Ÿ“ Ann Arbor๐Ÿ“ Cleveland๐Ÿ“ Portland Novelty Nobility, Inc. ยท Tests: NN3201 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors NCT05970497Phase 1, Phase 215 sites๐Ÿ“ Los Angeles๐Ÿ“ Rancho Santa Margarita๐Ÿ“ Weston Krystal Biotech, Inc. ยท Tests: KB707, Opdualag, KEYTRUDA ยฎ( Pembrolizumab) A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body NCT06413680Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ North Haven Regeneron Pharmaceuticals ยท Tests: REGN10597, Cemiplimab AMT-253 in Patients With Advanced Solid Tumours NCT06209580Phase 1, Phase 21 site๐Ÿ“ Beijing Multitude Therapeutics Inc. ยท Tests: AMT-253 for injection Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer NCT05098210Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Neoantigen Peptide Vaccine, Nivolumab, Poly ICLC, Echocardiography Test, Multigated Acquisition Scan Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma NCT05655312Phase 1, Phase 216 sites๐Ÿ“ Orange๐Ÿ“ Jacksonville๐Ÿ“ Miami Perspective Therapeutics ยท Tests: [203Pb]VMT01, [212Pb]VMT01, Nivolumab AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors NCT07027488Phase 11 site๐Ÿ“ New Haven Yale University ยท Tests: AB821 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab
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