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30 recruiting trials

for Amyloidosis, Primary

SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders NCT07850284n/a1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Non-Interventional Study A Phase II Study to Evaluate the Efficacy and Safety of Teclistamab in Combination With Daratumumab (Tec-Dara) in Newly Diagnosed Multiple Myeloma With Concurrent Light Chain Amyloidosis (MM+AL). NCT07638683Phase 21 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Teclistamab Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis NCT06699394NA2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Teclistamab (Tec) Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis NCT06971380Phase 21 site๐Ÿ“ Jerusalem Polina Stepensky ยท Tests: HBI0101 CART Promoting Diagnosis and Management of AL in Italy (ProDigALIty) NCT06383143n/a4 sites๐Ÿ“ Bari๐Ÿ“ Catania๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: no intervention Essen Amyloidosis Registry NCT06887283n/a1 site๐Ÿ“ Essen University Hospital, Essen Collection of Samples and Clinical Data From Patients With Amyloid Diseases NCT00898235n/a1 site๐Ÿ“ Boston Boston Medical Center ยท Tests: clonality analysis, polymerase chain reaction, protein analysis, biologic sample preservation procedure, laboratory bioโ€ฆ Rapid dFLC Response Predict CHR in AL Amyloidosis NCT06627309n/a8 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Dara IV, Bortezomib (drug), Dexamethasone, Cyclophosphamide (CTX), Dara SC Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients with MIDD NCT06418477Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Guangzhou Peking University People's Hospital ยท Tests: Dara-CyBorD Screening for AL Amyloidosis in Smoldering Multiple Myeloma NCT06365060n/a13 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Tufts Medical Center Daratumumab for Patients With Light Chain Amyloidosis NCT06376214NA1 site๐Ÿ“ Nanjing Nanjing University School of Medicine ยท Tests: Dratumumab / Hyaluronidase Injection [Darzalex Faspro], Pomalidomide 4 MG, autologous stem cell transplantation (ASCT) Study Evaluating the Efficacy and Safety of CM336 Injection in the Treatment of Light-Chain Amyloidosis NCT07039578Phase 22 sites๐Ÿ“ Beijing๐Ÿ“ Tianjin Keymed Biosciences Co.Ltd ยท Tests: CM336 Injection(Low dose group), CM336 Injection(High dose group) A Registry of AL Amyloidosis (ReAL) NCT04839003n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis NCT06342466Phase 21 site๐Ÿ“ Beijing Jin Lu, MD ยท Tests: Bortezomib, Pomalidomide, Dexamethasone A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis NCT05652335Phase 129 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ San Francisco Janssen Research & Development, LLC ยท Tests: JNJ-79635322 The Swedish BioFINDER 2 Study NCT03174938NA2 sites๐Ÿ“ ร„ngelholm๐Ÿ“ Malmรถ Skane University Hospital ยท Tests: Flutemetamol F18 Injection, [18F]-RO6958948, Elecsys (Roche) Abeta42, Ttau and Ptau, Lumipulse (Fujirebio) Abeta42, Ttaโ€ฆ The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas NCT07285044Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Cancer Therapeutic Procedure, Cancer Therapeutic Procedure, Questionnaire Administration The Norwegian Immunotherapy in Multiple Myeloma Study NCT06855121n/a23 sites๐Ÿ“ Arendal๐Ÿ“ ร…lesund๐Ÿ“ Bergen St. Olavs Hospital ยท Tests: Teclistamab, Elranatamab, Ciltacabtagene Autoleucel, Talquetamab, Idecabtagene vicleucel Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis NCT07250269Phase 19 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Gracell Biotechnologies (Shanghai) Co., Ltd. ยท Tests: GC012F Injection Hungarian National Systemic Amyloidosis Registry NCT07689331n/a12 sites๐Ÿ“ Balatonfรผred๐Ÿ“ Budapest๐Ÿ“ Budapest Semmelweis University A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA) NCT06205953n/a6 sites๐Ÿ“ Heidelberg๐Ÿ“ Pavia๐Ÿ“ Utrecht Fondazione IRCCS Policlinico San Matteo di Pavia Evaluation of Skin Tests in Biotherapy Allergies NCT06971848NA1 site๐Ÿ“ Angers University Hospital, Angers ยท Tests: Drug skin tests (investigating hypersensitivity to a biotherapy) The Italian Transthyretin Amyloidosis Web-Network NCT05444920n/a30 sites๐Ÿ“ Legnano๐Ÿ“ Orbassano๐Ÿ“ Ancona Fondazione IRCCS Policlinico San Matteo di Pavia Investigating the Pathogenic Role of N-glycosylation in AL Amyloidosis: Molecular Bases, Diagnosis, and Treatment NCT07448779n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis NCT05951816Phase 11 site๐Ÿ“ Knoxville University of Tennessee Graduate School of Medicine ยท Tests: 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m., 99mTc-Pyrophosphate Molecular Imaging of Primary Amyloid Cardiomyopathy NCT02641145NA1 site๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: F-18 florbetapir/C-11 acetate PET, MRI, N-13 ammonia PET Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research NCT07085559EARLY Phase 11 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Metabolically Armed BCMA CAR-T cells. DapagliFLOzin in Renal AL Amyloidosis (FLORAL) NCT06420167Phase 21 site๐Ÿ“ Detroit Barbara Ann Karmanos Cancer Institute ยท Tests: Dapagliflozin Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis NCT06022939Phase 3117 sites๐Ÿ“ Goodyear๐Ÿ“ Tucson๐Ÿ“ Tucson SWOG Cancer Research Network ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrowโ€ฆ Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis NCT07335887Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Xi'an Peking University People's Hospital ยท Tests: sonrotoclax, Daratumumab, Dexamethasone
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