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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Bipolar 1 Disorder

An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania NCT07288320Phase 211 sites📍 Little Rock📍 Cerritos📍 Garden Grove Neurocrine Biosciences · Tests: NBI-1117568, Placebo A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3) NCT06929273Phase 3184 sites📍 Glendale📍 Scottsdale📍 Tucson Bristol-Myers Squibb · Tests: KarXT, Lithium, Valproate, Lamotrigine Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. NCT07494305Phase 226 sites📍 Bentonville📍 Little Rock📍 Bellflower LB Pharmaceuticals Inc. · Tests: LB-102, Placebo A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar Disorder NCT07071532Phase 12 sites📍 Los Alamitos📍 Grayslake AbbVie · Tests: ABBV-932, Itraconazole Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder NCT07213466Phase 41 site📍 Rochester Mayo Clinic · Tests: Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination) Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder NCT06373016NA3 sites📍 Belmont📍 Charlestown📍 Stony Brook Stony Brook University · Tests: Glucose, Ketones Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression NCT07026461Phase 42 sites📍 Örebro📍 Uppsala Region Örebro County · Tests: repetitive transcranial magnetic stimulation, intermittent theta burst stimulation Feasibility and Preliminary Results of the Efficacy of Blue-Blocking Glasses on Manic Symptoms in Bipolar Disorder NCT07194278NA1 site📍 Paris Centre Hospitalier St Anne · Tests: Blue-blocking glasses Safety and Tolerability of Open-Labeled Iloperidone in Adolescents NCT05648591Phase 411 sites📍 Dothan📍 Little Rock📍 Denver Vanda Pharmaceuticals · Tests: Iloperidone Safety and Feasibility of DBS for Bipolar Depression NCT07745374NA1 site📍 New York Icahn School of Medicine at Mount Sinai · Tests: Medtronic Percept PC DBS system Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder NCT05303064Phase 347 sites📍 Dothan📍 Little Rock📍 Encino Alkermes, Inc. · Tests: OLZ/SAM, Olanzapine SYNCED - SYNChronized Eating in Bipolar Depression Study NCT06560957NA1 site📍 Ottawa University of Ottawa · Tests: Time restricted eating, Eating ad libitum with nutritional counselling Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral Cariprazine NCT07185815Phase 1, Phase 26 sites📍 Ahmedabad📍 Ahmedabad📍 Beersheba Mapi Pharma Ltd. · Tests: Cariprazine Depot, Cariprazine Depot, Cariprazine Depot MTD, Oral Cariprazine 3 mg/day A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder NCT07540338Phase 1, Phase 21 site📍 Boston Alzamend Neuro, Inc. · Tests: AL001, Lithium carbonate A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine NCT07140913Phase 3104 sites📍 Bentonville📍 Little Rock📍 Bellflower Bristol-Myers Squibb · Tests: Xanomeline/Trospium Chloride, Placebo Melatonin and Response to Lithium NCT05878730n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: urine collection, Level of Proteins, Level of mRNA and miRNA, Level of plasmatic and intraerythrocytic lithium A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder. NCT04777357Phase 381 sites📍 Bentonville📍 Anaheim📍 Beverly Hills AbbVie · Tests: Cariprazine, Placebo Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups NCT07212075n/a3 sites📍 Bad Mergentheim📍 Bad Mergentheim📍 Würzburg Forschungsinstitut der Diabetes Akademie Mergentheim Socio-cognitive and Biological Responses to Maltreatment NCT07101107n/a1 site📍 Innsbruck Medical University Innsbruck Neuromodulation of Mood Switch Circuitry in Bipolar Disorder NCT07680153Phase 41 site📍 New York Weill Medical College of Cornell University · Tests: MagVenture MagPro TMS system, Sham Stimulation A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) NCT06951711Phase 385 sites📍 Little Rock📍 Rogers📍 Culver City Bristol-Myers Squibb · Tests: KarXT, Placebo NMDA Receptor Modulation for the Treatment of Bipolar I Disorder NCT05977023Phase 21 site📍 Taichung China Medical University Hospital · Tests: NMDAE, Placebo Cap Ketogenic and Nutritional Interventions for First Episode Bipolar Disorder NCT06221852NA1 site📍 Belmont Mclean Hospital · Tests: Ketogenic diet, Dietary Guidelines for Americans A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder NCT06951698Phase 374 sites📍 Bentonville📍 Little Rock📍 Anaheim Bristol-Myers Squibb · Tests: KarXT, Placebo Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder NCT05837104Phase 21 site📍 Belmont Mclean Hospital · Tests: Magnesium vitamin B6, Placebo A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder NCT06696755Phase 233 sites📍 Huntsville📍 Chandler📍 Tucson AbbVie · Tests: Icalcaprant, Placebo for Icalcaprant Children's Bipolar Network Treatment Trial I NCT05427123n/a4 sites📍 Los Angeles📍 Aurora📍 Pittsburgh University of California, Los Angeles · Tests: Medication or psychosocial treatment CLOZAPINE Response in Biotype-1 NCT04580134Phase 45 sites📍 Hartford📍 Athens📍 Chicago University of Texas Southwestern Medical Center · Tests: clozapine, risperidone Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services NCT06740383n/a6 sites📍 Hartford📍 Athens📍 Chicago Beth Israel Deaconess Medical Center LHC-CIDI-5 in Hong Kong NCT06804525n/a1 site📍 Hong Kong The University of Hong Kong · Tests: CIDI-5, LHC-CIDI-5
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