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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Cholangiocarcinoma Non-resectable

Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery NCT04891289Phase 211 sites📍 Bethesda📍 St Louis📍 Basking Ridge Memorial Sloan Kettering Cancer Center · Tests: Gemcitabine, Oxaliplatin, Dexamethasone, Floxuridine (FUDR), Implanted Medical Device Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma NCT07780838Phase 21 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Durvalumab, Gemcitabine A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites📍 Phoenix📍 Jacksonville📍 Tampa Elevar Therapeutics · Tests: Lirafugratinib Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer NCT03942328Phase 1, Phase 21 site📍 Rochester Mayo Clinic · Tests: Atezolizumab, Bevacizumab, External Beam Radiation Therapy, Pheresis, Pneumococcal 13-valent Conjugate Vaccine Liver Transplantation in Intrahepatic Cholangiocarcinoma NCT06140134n/a2 sites📍 Newark📍 Newark Rutgers, The State University of New Jersey · Tests: Liver Transplant TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors NCT06487663NA1 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: TACE with ICI CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites📍 Denver📍 Chicago📍 Grand Rapids Context Therapeutics Inc. · Tests: CT-95 Novel Subtypes and Treatment Strategies of Patients with Unresectable Combined Hepatocellular Cholangiocarcinoma Based on Multimodal Data NCT06849180n/a1 site📍 Nanjing Zhongda Hospital · Tests: Interventional therapies combined with or without systemic drugs Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy NCT06375915Phase 24 sites📍 Bergamo📍 Milan📍 Naples Francesco De Cobelli · Tests: radioembolization with Y-90, Durvalumab, Cisplatin, Gemcitabine Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma NCT06175845NA9 sites📍 Berlin📍 Bonn📍 Chemnitz Universitätsklinikum Hamburg-Eppendorf · Tests: Intraductal biliary radiofrequency ablation Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments NCT06862934n/a1 site📍 Milan Fondazione IRCCS Istituto Nazionale dei Tumori, Milano A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites📍 Birmingham📍 Los Angeles📍 Miami Astellas Pharma Global Development, Inc. · Tests: ASP546C Pemigatinib + Afatinib in Advanced Refractory Solid Tumors NCT06302621Phase 11 site📍 Boston Massachusetts General Hospital · Tests: Afatinib, Pemigatinib Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extra- and Intrahepatic Cholangiocarcinoma NCT06440993Phase 212 sites📍 Aachen📍 Bonn📍 Cologne Institut für Klinische Krebsforschung IKF GmbH at Krankenha… · Tests: Gemcitabine, Cisplatin, Durvalumab, ID-RFA Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Perihilar Cholangiocarcinoma. A Prospective Multicenter Study. NCT04378023n/a1 site📍 Barcelona Hospital Vall d'Hebron · Tests: Neoadjuvant Chemo-radiotherapy, Liver Transplantation Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma NCT07030140Phase 21 site📍 Jinan Jinbo Yue · Tests: Stereotactic Body Radiotherapy (SBRT), Tislelizumab, Gemcitabine, Cisplatin or Oxaliplatin Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma NCT06058663Phase 11 site📍 Jacksonville Mayo Clinic · Tests: Angiography, Biopsy, Biospecimen Collection, Computed Tomography, Durvalumab Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949Phase 21 site📍 Boston Beth Israel Deaconess Medical Center · Tests: Gemcitabine, Cisplatin, Durvalumab, Yttrium-90 PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma NCT05286814Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Dexamethasone, PDS01ADC, Intera 3000 Hepatic Artery Infusion Pump (HAIP), Floxuridine D-TACE-HAIC Combined With Envafolimab and Lenvatinib for Unresectable ICC NCT06643208n/a1 site📍 Fuzhou Fujian Provincial Hospital · Tests: TACE-HAIC, Envafolimab and Lenvatinib Combined HAIC, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma NCT06192797Phase 21 site📍 Wuhan Tongji Hospital · Tests: HAIC, Lenvatinib plus pucotenlimab Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma NCT06298968Phase 21 site📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: combined therapy using gemcitabine and cisplatin chemotherapy, Lenvatinib and Adebrelimab Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer NCT06274879Phase 24 sites📍 Bern📍 Geneva📍 Lucerne Insel Gruppe AG, University Hospital Bern · Tests: Gemcitabin, Cisplatin and Durvalumab, Biliary Radiofrequency Ablation, Endoscopic Retrograde Cholangio-Pancreatography … Pemigatinib Plus PD-1 Inhibitor With or Without Chemotherapy in FGFR2 Fusion/Rearrangement-Positive Cholangiocarcinoma NCT07786766Phase 21 site📍 Beijing Haitao Zhao, MD · Tests: Pemigatinb, PD-1 inhibitors, Chemotherapy A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) NCT07221253Phase 3183 sites📍 Birmingham📍 Phoenix📍 Tucson AstraZeneca · Tests: Rilvegostomig, Durvalumab, Gemcitabine/Cisplatin Treatment of Non-resectable Bile Duct Cancer with Radiofrequency Ablation or Photodynamic Therapy NCT05551299Phase 420 sites📍 Aachen📍 Augsburg📍 Berlin University of Leipzig · Tests: Photosensitizer, Radiofrequency ablation (RFA) Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study NCT05342194Phase 31 site📍 Shanghai Shanghai Junshi Bioscience Co., Ltd. · Tests: Toripalimab, Lenvatinib mesylate capsules, Placebo IV, Oral placebo, Oxaliplatin for injection A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma NCT05678270Phase 244 sites📍 Hefei📍 Beijing📍 Beijing Beijing InnoCare Pharma Tech Co., Ltd. · Tests: ICP-192 LIver Transplantation for Non-Resectable Intrahepatic CholAngiocarcinoma (LIRICA) NCT06098547NA1 site📍 Padova Azienda Sanitaria Ospedaliera · Tests: Liver transplantation A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC NCT06925516Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: Apatinib and Adebrelimab in Combination With chemotherapy
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