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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Early Stage Triple-Negative Breast Carcinoma

CtDNA Based MRD Testing for NAC Monitoring in TNBC NCT06230185n/a14 sites📍 Tucson📍 Aurora📍 Washington D.C. Personalis Inc. A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs) NCT07743190Phase 22 sites📍 Syracuse📍 Charleston Medical University of South Carolina · Tests: Carboplatin, Paclitaxcel, Pembrolizumab Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer NCT06220214EARLY Phase 11 site📍 Stony Brook Alison Stopeck · Tests: CEDM, CEDBT, Omnipaque 350mgI/mL Solution for Injection A Study to Explore Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of Novel Therapeutics in Patients With Early Relapsed Metastatic Triple-negative Breast Cancer NCT06508216Phase 1, Phase 21 site📍 Villejuif Gustave Roussy, Cancer Campus, Grand Paris · Tests: Dato-DXd, Durvalumab A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer NCT07768436Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: CMF Regimen, Paclitaxel SBRT Combined With PD-1 Inhibitor and Chemotherapy in Early-stage TNBC NCT06627712Phase 31 site📍 Sichuan West China Hospital · Tests: SBRT+PD-1 Inhibitor + Chemotherapy, PD-1 Inhibitor + Chemotherapy Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03) NCT06797635Phase 217 sites📍 Santa Monica📍 Skokie📍 Billings Merck Sharp & Dohme LLC · Tests: Patritumab deruxtecan, Pembrolizumab, Paclitaxel, Carboplatin, Doxorubicin hydrochloride Circulating Tumor DNA Guided Boost Therapy in Early Triple Negative Breast Patients With Residual Disease After Neoadjuvant Therapy NCT06992336Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: Apatinib, Camrelizumab, Capecitabine EvoLution of Neoadjuvant TreatMent in 'Triple-negative' or 'HER-2-positive' Breast Cancer Diagnosed in the EaRly Phase NCT06894173n/a29 sites📍 Aviano📍 Ancona📍 Avellino Fondazione Policlinico Universitario Agostino Gemelli IRCCS Ph2 Study for Optimization of Adjunct Systemic Therapy in HER2+ Patients, MolecularPCR Trial NCT07407920Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Biospecimen Collection, Hormone Therapy, Pembrolizumab, Pertuzumab, Trastuzumab TIL-Driven De-escalated Chemotherapy in Stage I-II TNBC NCT07074106Phase 25 sites📍 Brasília📍 Curitiba📍 Rio de Janeiro D'Or Institute for Research and Education · Tests: Carboplatin and a Taxane Phase II Trial of Ivonescimab in Combination With Carboplatin + Docetaxel in Patients With Early-Stage Triple Negative Breast Cancer NCT07017673Phase 24 sites📍 Los Angeles📍 Los Angeles📍 Pasadena Cedars-Sinai Medical Center · Tests: Ivonescimab, Carboplatin, Docetaxel Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer NCT04768426Phase 21 site📍 Stanford Stanford University · Tests: Capecitabine Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer NCT05929768Phase 3963 sites📍 Birmingham📍 Anchorage📍 Anchorage SWOG Cancer Research Network · Tests: Biospecimen Collection, Carboplatin, Cyclophosphamide, Docetaxel, Doxorubicin Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies NCT07211178n/a16 sites📍 Birmingham📍 Whittier📍 Weston Tempus AI · Tests: There are no interventions in this observational study. Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer NCT06768931Phase 25 sites📍 Lanzhou📍 Dongguan📍 Guangzhou Sun Yat-sen University · Tests: Biolosion (oral probiotic compound preparation) Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer NCT05020860Phase 22 sites📍 Houston📍 Houston Baylor Breast Care Center · Tests: Paclitaxel, Carboplatin, Trastuzumab, Pertuzumab, Doxorubicin Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer NCT04959474NA1 site📍 Philadelphia Thomas Jefferson University · Tests: Best Practice, Stereotactic Body Radiation Therapy, Resection, Sentinel Lymph Node Biopsy, Dietary Intervention Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer NCT06324240Phase 14 sites📍 Atlanta📍 Atlanta📍 Atlanta Emory University · Tests: Ipilimumab, Pembrolizumab, Vaccine Therapy Early Detection of Triple Negative Breast Cancer Relapse (CUPCAKE) NCT06225505NA13 sites📍 Avignon📍 Bordeaux📍 Clermont-Ferrand Institut Curie · Tests: ctDNA monitoring, 68Ga-FAPI-46-PET-CT I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites📍 Birmingham📍 Scottsdale📍 Tucson QuantumLeap Healthcare Collaborative · Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Tras… MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC NCT07327021Phase 22 sites📍 Tel Aviv📍 Tel Litwinsky Tel-Aviv Sourasky Medical Center · Tests: Treatment De-Escalation and Early Surgery A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) NCT06966700Phase 3331 sites📍 Gilbert📍 Phoenix📍 Tucson Merck Sharp & Dohme LLC · Tests: Sacituzumab tirumotecan, Pembrolizumab, Rescue Medication, Carboplatin, Paclitaxel Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer NCT04790305Phase 434 sites📍 Hefei📍 Hefei📍 Beijing Fudan University · Tests: Huaier Granule PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC NCT06245889Phase 22 sites📍 Baltimore📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Paclitaxel, Carboplatin, Pembrolizumab, Doxorubicin, Cyclophosphamide Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy NCT05582499Phase 21 site📍 Shanghai Fudan University · Tests: Dalpiciclib, Pyrotinib, SHR-A1811, SHR-1316, Camrelizumab Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab NCT05812807Phase 3846 sites📍 Birmingham📍 Fairhope📍 Mobile Alliance for Clinical Trials in Oncology · Tests: Pembrolizumab, Patient Observation, Biopsy, Biospecimen Collection, Questionnaire Administration FMD and Neoadjuvant Chemo-immunotherapy in TNBC NCT07378306Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Fasting-mimicking diet, Chemotherapy, Toripalimab DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast Cancer NCT05504707Phase 11 site📍 Tampa H. Lee Moffitt Cancer Center and Research Institute · Tests: HER2 - primed Dendritic cells, HER3 - primed Dendritic cells Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer NCT06606730Phase 32 sites📍 Brussels📍 Villejuif UNICANCER · Tests: Pembrolizumab, Deescalation
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