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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for First-line Treatment of Metastatic Pancreatic Cancer

A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer NCT06953999Phase 33 sites📍 Harbin📍 Shanghai📍 Hangzhou Akeso · Tests: Ivonescimab, AK117, Albumin-bound Paclitaxel, Gemcitabine, Ivonescimab, AK117 Placebo, Albumin-bound Paclitaxel, Gemcit… Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer Patients NCT05065801Phase 28 sites📍 Grenoble📍 Saint-Etienne📍 Reims Institut du Cancer de Montpellier - Val d'Aurelle · Tests: GEMBRAX/FOLFIRINOX Arm A, FOLFIRINOX Arm B A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer NCT07409272Phase 379 sites📍 Tucson📍 Fort Smith📍 Fullerton Astellas Pharma Global Development, Inc. · Tests: Setidegrasib, Oxaliplatin, Leucovorin, Irinotecan, fluorouracil Irinotecan Hydrochloride Liposome Injection (II)in Combination With Oxaliplatin, 5-FU/LV Versus AG for First-line Treatment of Metastatic Pancreatic Cancer NCT07238283Phase 31 site📍 Beijing Jiangsu HengRui Medicine Co., Ltd. · Tests: Irinotecan Hydrochloride Liposome Injection (II); Oxaliplatin; 5Fluorouracil; Calcium folinate, nab-paclitaxel; gemcita… Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma NCT07805954Phase 35 sites📍 Phoenix📍 Scottsdale📍 Jacksonville Revolution Medicines, Inc. · Tests: daraxonrasib, gemcitabine, nab-paclitaxel, zoldonrasib HRS 4642 Injection Combined With AG Versus Placebo Combined With AG Therapy in First-Line Advanced or Metastatic Pancreatic Cancer NCT07232875Phase 31 site📍 Shanghai Jiangsu HengRui Medicine Co., Ltd. · Tests: HRS-4642 + AG, HRS-4642 placebo + AG A Clinical Study on the First-line Treatment of Metastatic Pancreatic Cancer With TQB2916 Injection Combined With Gemcitabine Hydrochloride for Injection and Paclitaxel for Injection (Albumin-bound Type) NCT06962267Phase 21 site📍 Beijing Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Phar… · Tests: TQB2916 Injection, Chemotherapy Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer NCT06454448Phase 1, Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Adebrelimab;decitabine; Efficacy of First-Line Gemcitabine Chemotherapy in GemCore+ Metastatic Pancreatic Adenocarcinoma Patients NCT06046794NA1 site📍 Marseille Institut Paoli-Calmettes · Tests: Analyze of GemCore status A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer NCT06361888Phase 2, Phase 352 sites📍 Hefei📍 Beijing📍 Beijing Hutchmed · Tests: Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine, Nab-paclitaxel Plus Gemcitabine, Surufatinib w… BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma NCT07226856Phase 23 sites📍 Scottsdale📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Gemcitabine, Imzokitug Adebrelimab and Chidamide for Pancreatic Cancer NCT06584227Phase 21 site📍 Nanjing Liu Xiufeng · Tests: Adebrelimab and Chidamide Combined with Gemcitabine and S1 HRS-4642 With Nimotuzumab and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer Patients NCT06770452Phase 22 sites📍 Hangzhou📍 Hangzhou Zhejiang University · Tests: HRS-4642, Nimotuzumab, gemcitabine + nab-paclitaxel Clinical Study of TQB2868 Injection Combined With Anlotinib Capsule and Chemotherapy in the First-line Treatment of Metastatic Pancreatic Neoplasms NCT06767813Phase 27 sites📍 Zhengzhou📍 Zhengzhou📍 Nanjing Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Phar… · Tests: TQB2868 injection, Gemcitabine injection, Albumin paclitaxel injection, Anlotinib capsules Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of Chemotherapy NCT05988814Phase 21 site📍 Dijon Centre Georges Francois Leclerc · Tests: FOLFIRINOX treatment NALIRIFOX+Adebrelimab+PULSAR for Advanced Pancreatic Cancer NCT07595172Phase 1, Phase 21 site📍 Chengdu West China Hospital · Tests: NALIRIFOX+Adebrelimab, PULSAR NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC NCT06405490Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Nanoliposomal Irinotecan+Oxaliplatin +Capecitabine+Cadonilimab Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 ) NCT07621718Phase 319 sites📍 Phoenix📍 Tucson📍 New Haven Revolution Medicines, Inc. · Tests: Zoldonrasib, Placebo, Oxaliplatin, Leucovorin (Calcium Folinate), 5-Fluorouracil QL1706 Plus Chidamide, AG as First-line Treatment for Metastatic Pancreatic Cancer NCT06951997Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: QL1706, Chidamide, Gemcitabine, Nab-paclitaxel Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer NCT05218889Phase 1, Phase 21 site📍 Beijing Chinese PLA General Hospital · Tests: surufatinib + camrelizumab + nab-paclitaxel + S-1, nab-paclitaxel + gemcitabine Polymeric Micellar Paclitaxel for Metastatic Pancreatic Cancer NCT06752811Phase 32 sites📍 Nanjing📍 Shanghai Shanghai Yizhong Pharmaceutical Co., Ltd. · Tests: paclitaxel polymeric micelles for injection, Gemcitabine Hydrochloride for Injection, Paclitaxel for Injection (albumin… ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer NCT07444541Phase 1, Phase 23 sites📍 Los Angeles📍 Plantation📍 San Antonio Anova Innovation Limited · Tests: ANO31905, AG [gemcitabine+nab-paclitaxel], mFOLFIRINOX [Oxaliplatin+irinotecan+leucovorin+fluorouracil] Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer NCT06572813Phase 1, Phase 21 site📍 Hangzhou First Affiliated Hospital of Zhejiang University · Tests: Bortezomib Injection, Sintilimab, mFOLFIRINOX Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma NCT07562152Phase 370 sites📍 Huntsville📍 Phoenix📍 Duarte Immuneering Corporation · Tests: Atebimetinib, GnP, mGnP A Single-center, Prospective, Two Cohort Study of Surufatinib Combined With AG or AG in the First-line Treatment of Locally Advanced or Metastatic Pancreatic Cancer NCT05969171Phase 21 site📍 Shanghai Fudan University · Tests: Surufatinib, gemcitabine, nab-paclitaxel, Nab-paclitaxel, gemcitabine Albumin-Bound Paclitaxel and Gemcitabine With or Without S-1 as First-Line Treatment for Advanced Pancreatic Cancer NCT06789679Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Gemcitabine, albumin-bound paclitaxel, S-1, Gemcitabine, albumin-bound paclitaxel Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer NCT06491472Phase 21 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: Ivonescimab, Gemcitabine, Nab paclitaxel, SBRT Chemotherapy For Metastatic Grade 3 Poorly Differentiated NEuroendocrine Carcinoma Of GastroEnteroPancreatic And Unknown Primary NCT04325425Phase 26 sites📍 Caen📍 Dijon📍 Dijon Centre Hospitalier Universitaire Dijon · Tests: FOLFOXIRI Protocol, Cisplatin injection Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI NCT06333314Phase 222 sites📍 Angers📍 Avignon📍 Besançon UNICANCER · Tests: Dostarlimab, Chemotherapy A Study of AK104 With Chemotherapy as First-line Treatment in Patients With Advanced Pancreatic Cancer NCT05859750Phase 27 sites📍 Beijing📍 Guangzhou📍 Wuhan Akeso · Tests: AK104, AK104, Gemcitabine, Nab-Paclitaxel, Liposomal Irinotecan, Oxaliplatin, 5-Fluorouracil/Calcium folinate
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