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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Generalized Myasthenia Gravis

A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE) NCT07647510Phase 34 sites๐Ÿ“ Pasadena๐Ÿ“ Boca Raton๐Ÿ“ Fayetteville Dianthus Therapeutics ยท Tests: Claseprubart, Placebo, Claseprubart, Placebo A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG) NCT06987539Phase 214 sites๐Ÿ“ Chicago๐Ÿ“ Philadelphia๐Ÿ“ Austin Amgen ยท Tests: Inebilizumab Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs) NCT04202341n/a51 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Fresno Alexion Pharmaceuticals, Inc. GC012F Injection in the Treatment of Refractory Generalized Myasthenia Gravis(24103) NCT07058298EARLY Phase 11 site๐Ÿ“ Wuhan Daishi Tian ยท Tests: GC012F injection Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis NCT04833894Phase 2, Phase 325 sites๐Ÿ“ Chicago๐Ÿ“ Chapel Hill๐Ÿ“ Charlottesville argenx ยท Tests: Efgartigimod IV Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG) NCT07596784Phase 310 sites๐Ÿ“ Beijing๐Ÿ“ Changchun๐Ÿ“ Fuzhou Alexion Pharmaceuticals, Inc. ยท Tests: Ravulizumab Efficacy and Safety of Tocilizumab in the Treatment of Generalized Myasthenia Gravis NCT05067348Phase 26 sites๐Ÿ“ Beijing๐Ÿ“ Changsha๐Ÿ“ Xi'an Tang-Du Hospital ยท Tests: Tocilizumab Injectable Product ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis NCT07673627Phase 28 sites๐Ÿ“ Carlsbad๐Ÿ“ Miami๐Ÿ“ Las Vegas argenx ยท Tests: Empasiprubart IV, Placebo IV, Efgartigimod PH20 SC PFS Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health Phase 4 Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis NCT07246564Phase 412 sites๐Ÿ“ Beijing๐Ÿ“ Changchun๐Ÿ“ Changsha UCB Biopharma SRL ยท Tests: Rozanolixizumab Unhideยฎ Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research NCT04806620n/a1 site๐Ÿ“ Delafield Brain Inflammation Collaborative Evaluation of the Condition of Patients Receiving EARLY Ravulizumab and Admitted in ICU for gMG Crisis NCT07411963n/a8 sites๐Ÿ“ Nice๐Ÿ“ Bron๐Ÿ“ Garches Centre Hospitalier Universitaire de Nice ยท Tests: early use of Ravulizumab A Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis NCT06055959Phase 2, Phase 39 sites๐Ÿ“ Chicago๐Ÿ“ Denton๐Ÿ“ Milan UCB Biopharma SRL ยท Tests: Zilucoplan Evaluate the Benefit of Corticoid Sparing in Elderly With Generalized AntiRAch Myasthenia Gravis Treated With IV or SC Efgartigimod NCT07072988Phase 49 sites๐Ÿ“ Nice๐Ÿ“ Crรฉteil๐Ÿ“ Garches Centre Hospitalier Universitaire de Nice ยท Tests: Efgartigimod KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis NCT06193889Phase 2, Phase 322 sites๐Ÿ“ Los Angeles๐Ÿ“ Orange๐Ÿ“ Palo Alto Kyverna Therapeutics ยท Tests: Standard of Care Treatment, Standard lymphodepletion regimen, KYV-101 A Study to Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis NCT06688435Phase 11 site๐Ÿ“ Jinan CSPC ZhongQi Pharmaceutical Technology Co., Ltd. ยท Tests: SYS6020 injection, SYS6020 injection, SYS6020 injection Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis NCT06909253n/a11 sites๐Ÿ“ Bydgoszcz๐Ÿ“ Gdansk๐Ÿ“ Katowice AstraZeneca ยท Tests: Ravulizumab Zilucoplan for Severe gMG Exacerbations NCT07215949Phase 33 sites๐Ÿ“ Tampa๐Ÿ“ Kansas City๐Ÿ“ Columbus Miriam Freimer ยท Tests: Zilucoplanยฎ PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia Gravis NCT06607627Phase 313 sites๐Ÿ“ Washington D.C.๐Ÿ“ Norfolk๐Ÿ“ Joinville Alexion Pharmaceuticals, Inc. ยท Tests: Gefurulimab PANORAMA: Neuromuscular Organoids for Refractory AChR+ Myasthenia Gravis NCT07717281n/a1 site๐Ÿ“ Milan Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis NCT06371040Phase 11 site๐Ÿ“ Xi'an Ting Chang, MD ยท Tests: CD19-BCMA Targeted CAR-T Dose 1, CD19-BCMA Targeted CAR-T Dose 2, CD19-BCMA Targeted CAR-T Dose 2 Clinical Study of Cizutamig in Generalized Myasthenia Gravis (gMG) NCT07215650Phase 110 sites๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Candid Therapeutics ยท Tests: Cizutamig A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis NCT04951622Phase 3112 sites๐Ÿ“ Paradise Valley๐Ÿ“ Scottsdale๐Ÿ“ Los Angeles Janssen Research & Development, LLC ยท Tests: Nipocalimab, Placebo, Nipocalimab SC-LIV RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis NCT06359041Phase 1, Phase 217 sites๐Ÿ“ Orange๐Ÿ“ Sacramento๐Ÿ“ San Francisco Cabaletta Bio ยท Tests: CABA-201, CABA-201 Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad) NCT06463587Phase 3154 sites๐Ÿ“ Phoenix๐Ÿ“ Longmont๐Ÿ“ Farmington Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of โ€ฆ ยท Tests: Placebo, Cladribine Low Dose, Cladribine High Dose ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis NCT07294170n/a37 sites๐Ÿ“ Carlsbad๐Ÿ“ Miami๐Ÿ“ Miami argenx ยท Tests: Efgartigimod IV, Empasiprubart IV, Placebo IV, Efgartigimod PH20 SC PFS Myasthenia Gravis Foundation of America Global MG Patient Registry NCT06617741n/a1 site๐Ÿ“ Westborough Myasthenia Gravis Foundation of America A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG) NCT06909214Phase 418 sites๐Ÿ“ La Jolla๐Ÿ“ Rancho Mirage๐Ÿ“ Boca Raton argenx ยท Tests: Efgartigimod PH20 SC A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab NCT07221838Phase 412 sites๐Ÿ“ Chicago๐Ÿ“ Schaumburg๐Ÿ“ Neptune City Alexion Pharmaceuticals, Inc. ยท Tests: Oral Corticosteroid Tapering Schedule, Ravulizumab, Prednisone/Prednisolone A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis NCT07250750Phase 1, Phase 225 sites๐Ÿ“ Altamonte Springs๐Ÿ“ Boca Raton๐Ÿ“ Naples ImmunAbs Inc. ยท Tests: IM-101 Part A, Placebo Part A, IM-101 Part B, Placebo Part B
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