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25 recruiting trials

for Geographic Atrophy Secondary to Age-Related Macular Degeneration

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration NCT06662162NA13 sites๐Ÿ“ Poway๐Ÿ“ Manchester๐Ÿ“ Lemont i-Lumen Scientific AUS PTY LTD ยท Tests: i-Lumen AMD SGLT2 Inhibitors in Geographic Atrophy NCT07174687Phase 21 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: Dapagliflozin, Matching Placebo A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) NCT06635148Phase 2, Phase 3104 sites๐Ÿ“ Tucson๐Ÿ“ Fullerton๐Ÿ“ La Jolla Janssen Research & Development, LLC ยท Tests: JNJ-81201887, Sham Procedure Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic Atrophy Secondary to Dry AMD NCT07770828Phase 33 sites๐Ÿ“ Phoenix๐Ÿ“ Erie๐Ÿ“ McAllen Ocugen ยท Tests: OCU410 A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration NCT03178149Phase 120 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Palo Alto Astellas Institute for Regenerative Medicine ยท Tests: ASP7317, tacrolimus, trimethoprim-sulfamethoxazole, Acyclovir, Nystatin A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy NCT06541704Phase 3231 sites๐Ÿ“ Chandler๐Ÿ“ Phoenix๐Ÿ“ Phoenix Regeneron Pharmaceuticals ยท Tests: Pozelimab, Cemdisiran, Placebo Safety & Efficacy of Eyecyte-RPEโ„ข in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration. NCT06394232Phase 1, Phase 23 sites๐Ÿ“ Jฤlna๐Ÿ“ Delhi๐Ÿ“ Hyderabad Eyestem Research Pvt. Ltd. ยท Tests: Eyecyte-RPEโ„ข A Study to Assess the Efficacy and Safety of RO7965032 in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration NCT07851259Phase 25 sites๐Ÿ“ Walnut Creek๐Ÿ“ Winston-Salem๐Ÿ“ Erie Genentech, Inc. ยท Tests: RO7965032, Placebo A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA) NCT07144137n/a19 sites๐Ÿ“ Mountain View๐Ÿ“ Oak Forest๐Ÿ“ Springfield Complement Therapeutics Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration NCT04847635NA3 sites๐Ÿ“ Genova๐Ÿ“ Milan๐Ÿ“ Rome Ospedale San Raffaele ยท Tests: Pascal Synthesis 577 sub-threshold laser (Topcon Corporation, Tokyo, Japan), Pascal Synthesis 577 sham (Topcon Corporatโ€ฆ A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration NCT06765980Phase 1, Phase 24 sites๐Ÿ“ Erie๐Ÿ“ Ottawa๐Ÿ“ Tel Aviv Kriya Therapeutics, Inc. ยท Tests: VV-14295 Phase 2 Study of ADX-038 in Participants With Geographic Atrophy NCT06990269Phase 283 sites๐Ÿ“ Gilbert๐Ÿ“ Phoenix๐Ÿ“ Bakersfield ADARx Pharmaceuticals, Inc. ยท Tests: ADX-038, Placebo A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio NCT07215390Phase 278 sites๐Ÿ“ Gilbert๐Ÿ“ Mesa๐Ÿ“ Phoenix Apellis Pharmaceuticals, Inc. ยท Tests: APL-3007, pegcetacoplan (APL-2), APL-3007, pegcetacoplan (APL-2), Placebo, Syfovre A Study to Evaluate the Safety and Effect of TO-O-1007 Intravitreal Implant in Subjects With Geographic Atrophy NCT07668804Phase 1, Phase 23 sites๐Ÿ“ Hurstville๐Ÿ“ Sydney๐Ÿ“ Launceston Theratocular Biotek Co. ยท Tests: TO-O-1007 (low-dose), TO-O-1007 (high-dose), Sham injection Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy NCT07531927NA5 sites๐Ÿ“ Hamburg๐Ÿ“ Mรผnchen๐Ÿ“ Stuttgart Okuvision GmbH ยท Tests: Transcorneal electrical stimulation (TES) with the OkuStim 2 System, Transcorneal electrical stimulation (TES) with theโ€ฆ A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration NCT07441642Phase 259 sites๐Ÿ“ Huntington Beach๐Ÿ“ Sacramento๐Ÿ“ Santa Barbara Novartis Pharmaceuticals ยท Tests: FWY003, Placebo Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration NCT07160179Phase 1, Phase 25 sites๐Ÿ“ Carmel๐Ÿ“ Reno๐Ÿ“ Abilene AbbVie ยท Tests: ABBV-6628, SYFOVRE An Optimised GA Interventional Trial (Opti-GAIN) to Test if Treatment With CTx001 is Safe and Works for People With Geographic Atrophy (GA) NCT07392255Phase 1, Phase 28 sites๐Ÿ“ Carmel๐Ÿ“ Reno๐Ÿ“ Dallas Complement Therapeutics ยท Tests: CTx001 A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD NCT06659549Phase 224 sites๐Ÿ“ Beverly Hills๐Ÿ“ Walnut Creek๐Ÿ“ Hagerstown Galimedix Therapeutics Inc ยท Tests: GAL-101, Placebo A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 NCT05626114Phase 217 sites๐Ÿ“ Beverly Hills๐Ÿ“ Sacramento๐Ÿ“ San Francisco Genentech, Inc. ยท Tests: OpRegen A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration NCT07215234Phase 1, Phase 235 sites๐Ÿ“ Peoria๐Ÿ“ Scottsdale๐Ÿ“ Beverly Hills Sanofi ยท Tests: SAR446597, Sham Comparator A Study in Adults With Geographic Atrophy NCT07606365Phase 256 sites๐Ÿ“ Bakersfield๐Ÿ“ Beverly Hills๐Ÿ“ Aurora Sitala Bio LTD ยท Tests: STL303, Placebo Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants NCT07230834Phase 19 sites๐Ÿ“ Lakewood๐Ÿ“ East Weymouth๐Ÿ“ Austin Regeneron Pharmaceuticals ยท Tests: Pozelimab A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration NCT07029945Phase 1, Phase 217 sites๐Ÿ“ Gilbert๐Ÿ“ Phoenix๐Ÿ“ Hattiesburg Biojiva LLC ยท Tests: BRX011, Placebo A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD NCT07158775Phase 1, Phase 21 site๐Ÿ“ Edison Bionic Sight LLC ยท Tests: BS01, Sham procedure control
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