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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HER2-positive Gastric Cancer

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dongying Qilu Hospital of Shandong University ยท Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin IKS014 in Advanced Solid Tumors That Express HER2 NCT05872295Phase 113 sites๐Ÿ“ Newport Beach๐Ÿ“ Boston๐Ÿ“ Nashville Iksuda Therapeutics Ltd. ยท Tests: IKS014 Short Course Radiotherapy With Sequential Disitamab Vedotin Combined With S-1 and Sintilimab as Whole Course Neoadjuvant Therapy for HER2 Expressed Locally Progressive Gastric Cancer NCT06487429Phase 21 site๐Ÿ“ Wuhan Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: Short range radiotherapy with sequential Disitamab Vedotin combined with S-1 and xindilizumab KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy NCT05427383Phase 2, Phase 31 site๐Ÿ“ Beijing Shanghai JMT-Bio Inc. ยท Tests: KN026/Placbo Injection, Paclitaxel Injection, Docetaxel Injection, Irinotecan Injection Phase 2 Trial of KN026+KN046ยฑXELOX in HER2-positive Locally Advanced GC NCT06023758Phase 21 site๐Ÿ“ Beijing Peking University ยท Tests: KN026, KN046, XELOX A Phase โ…ข Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer NCT06764875Phase 3304 sites๐Ÿ“ Anchorage๐Ÿ“ Phoenix๐Ÿ“ Duarte AstraZeneca ยท Tests: Rilvegostomig, Trastuzumab deruxtecan, Trastuzumab, Pembrolizumab, 5-fluorouracil Gene Therapy for HER-Positive Cancer (SENTRY-HER2) NCT07192432Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ Jacksonville Vironexis Biotherapeutics Inc. ยท Tests: Dose Level 1, VNX-202, Dose Level 2, VNX-202, Dose Level 3, VNX-202, Dose Level 4, VNX-202 Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor NCT05523947Phase 1, Phase 219 sites๐Ÿ“ Boston๐Ÿ“ Nashville๐Ÿ“ Adelaide Yuhan Corporation ยท Tests: YH32367 A Study of BL-M17D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Lower Expression Gastrointestinal Cancer and Other Solid Tumors NCT06500052Phase 11 site๐Ÿ“ Guangzhou Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-M17D1 IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer NCT07025889Phase 1, Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: IBI343, Sintilimab, Oxaliplatin, S-1 To Evaluate IAH0968 in Combination With CAPEOX in HER2-positive Gastric Cancer NCT06504732Phase 2, Phase 32 sites๐Ÿ“ Harbin๐Ÿ“ Shenyang SUNHO๏ผˆChina๏ผ‰BioPharmaceutical CO., Ltd. ยท Tests: IAH0968, Trastuzumab Injection Adjuvant Serplulimab and Trastuzuma and Chemotherapy in Her-2+ Gastric Cancer NCT05975749Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Serplulimab, Trastuzuma, Chemotherapy Disitamab Vedotin Plus Trastuzumab in Patients With HER2 Positive GC/GEJ Patiens NCT06572319Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Disitamab Vedotin(RC48) Plus Tratuzumab A Phase โ…ข Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer NCT06532006Phase 3208 sites๐Ÿ“ Anaheim๐Ÿ“ Los Alamitos๐Ÿ“ Greeley Shanghai Henlius Biotech ยท Tests: HLX22, Pembrolizumab, Trastuzumab, Oxaliplatin, Capecitabine Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease NCT06253650Phase 21 site๐Ÿ“ Milan Gruppo Oncologico del Nord-Ovest ยท Tests: Experimental, Control Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients NCT06650332Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: cadonilimab, Trastuzumab, XELOX, Disitamab Vedotin, mFOLFOX6 A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive Metastatic Gastroesophageal Adenocarcinoma (GEA) Patients NCT07176312Phase 220 sites๐Ÿ“ Berlin๐Ÿ“ Berlin๐Ÿ“ Bielefeld Institut fรผr Klinische Krebsforschung IKF GmbH at Krankenhaโ€ฆ ยท Tests: Zanidatamab, Pembrolizumab, mFOLFOX Developing ctDNA Guided Adjuvant Therapy for Gastrooesophageal Cancer NCT05965479Phase 214 sites๐Ÿ“ Guildford๐Ÿ“ Coventry๐Ÿ“ Belfast University of Southampton ยท Tests: Trastuzumab deruxtecan Fruquintinib Combined With Trastuzumab and XELOX as First-line Treatment in Patients With HER2-positive Advanced Gastric Cancer NCT07334431Phase 1, Phase 21 site๐Ÿ“ Zhengzhou Henan Cancer Hospital ยท Tests: fruquintinib๏ผ‹trastuzumab + XELOX M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. NCT06177041Phase 31 site๐Ÿ“ Beijing FutureGen Biopharmaceutical (Beijing) Co., Ltd ยท Tests: M108 monoclonal antibody, Placebo, Oxaliplatin, Capecitabine Trastuzumab, Bevacizumab with Paclitaxel for HER2-positive Gastric Cancer in a Second-line Therapy NCT05640830Phase 1, Phase 21 site๐Ÿ“ Seoul Kangbuk Samsung Hospital ยท Tests: trastuzumab, bevacizumab with paclitaxel (triple combination) Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors NCT03740256Phase 11 site๐Ÿ“ Houston Baylor College of Medicine ยท Tests: CAdVEC A Phase 1/1b Study of IAM1363 in HER2 Cancers NCT06253871Phase 153 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ Aurora Iambic Therapeutics, Inc ยท Tests: IAM1363 SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen NCT06123494Phase 31 site๐Ÿ“ Shanghai Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR-A1811, Ramucirumab / Paclitaxel/ Docetaxel/ Irinotecan A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer NCT07673887Phase 38 sites๐Ÿ“ Saint Louis Park๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Capecitabine, Folinic acid Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2 NCT07431281Phase 3314 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Anchorage AstraZeneca ยท Tests: Sonesitatug vedotin, Rilvegostomig, Nivolumab, Capecitabine, 5-Fluorouracil A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors NCT05150691Phase 1, Phase 2102 sites๐Ÿ“ Cerritos๐Ÿ“ Los Angeles๐Ÿ“ San Diego DualityBio Inc. ยท Tests: DB-1303/BNT323, Pertuzumab Injection, Ritonavir, Itraconazole At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer NCT05969860Phase 22 sites๐Ÿ“ Jacksonville๐Ÿ“ Grand Forks Mayo Clinic ยท Tests: Clinical Encounter, Home Health Encounter, Quality-of-Life Assessment, Questionnaire Administration Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma in China NCT06846996n/a40 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Daiichi Sankyo ยท Tests: Trastuzumab deruxtecan (T-DXd)
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