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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Hepatic Impairment

A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234 NCT07546760Phase 14 sites๐Ÿ“ Chandler๐Ÿ“ Rialto๐Ÿ“ Miami Lakes AstraZeneca ยท Tests: AZD6234, AZD9550 To Evaluate the Pharmacokinetics and Safety of TQ05105 Tablet in Hepatic Impairment Subjects NCT07480824Phase 12 sites๐Ÿ“ Luoyang๐Ÿ“ Jinan Chia Tai Tianqing Pharmaceutical Group Co., Ltd. ยท Tests: TQ05105 Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment NCT07036133Phase 14 sites๐Ÿ“ Cerritos๐Ÿ“ Chicago๐Ÿ“ Detroit Acrotech Biopharma Inc. ยท Tests: Pralatrexate Injection A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function NCT07269301Phase 13 sites๐Ÿ“ Lake Forest๐Ÿ“ Orlando๐Ÿ“ Tampa Pfizer ยท Tests: PF-07328948 A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems NCT07486102Phase 11 site๐Ÿ“ San Antonio Boehringer Ingelheim ยท Tests: BI 3000202 A Phase I Clinical Trial to Evaluate the Pharmacokinetic and Safety of Ammoxetine Hydrochloride Enteric-Coated Tablets in Participants With Mild Hepatic Impairment, Moderate Hepatic Impairment, and Normal Liver Function NCT07694843Phase 11 site๐Ÿ“ Suzhou CSPC ZhongQi Pharmaceutical Technology Co., Ltd. ยท Tests: ammoxetine hydrochloride enteric-coated tablets Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI) NCT06962332Phase 12 sites๐Ÿ“ Orlando๐Ÿ“ San Antonio Exelixis ยท Tests: Zanzalintinib A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers. NCT07401862Phase 13 sites๐Ÿ“ Orlando๐Ÿ“ San Antonio๐Ÿ“ Kistarcsa Eli Lilly and Company ยท Tests: LY3841136 Comparative PK Assessment Study of Casdatifan in Moderate Hepatically Impaired Participants Versus Matched Participants With Normal Hepatic Function NCT07751250Phase 11 site๐Ÿ“ San Antonio Arcus Biosciences, Inc. ยท Tests: Casdatifan A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function NCT07519135Phase 13 sites๐Ÿ“ Miami Lakes๐Ÿ“ Orlando๐Ÿ“ Tampa Pfizer ยท Tests: PF-08653944 Pharmacokinetics of Petrelintide in Participants With Impaired Hepatic Function NCT07682818Phase 13 sites๐Ÿ“ Wroclaw๐Ÿ“ Bratislava๐Ÿ“ Malacky Zealand Pharma ยท Tests: Petrelintide A Study of an IDH1m Inhibitor in Participants With IDH1-Mutated Malignancies and Hepatic or Renal Impairment NCT07006688Phase 120 sites๐Ÿ“ Atlanta๐Ÿ“ Columbus๐Ÿ“ Houston Servier Bio-Innovation LLC ยท Tests: Ivosidenib Oral Tablet The Liver Cirrhosis Cognitive Decline Scale (LiCCoS) NCT07418008n/a1 site๐Ÿ“ Ambฤla University of Malaya Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants NCT07250633Phase 13 sites๐Ÿ“ Chandler๐Ÿ“ Orlando๐Ÿ“ San Antonio Institut de Recherches Internationales Servier (I.R.I.S.) ยท Tests: Vorasidenib 20mg Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment NCT06740799Phase 13 sites๐Ÿ“ Miami๐Ÿ“ Miami๐Ÿ“ St. Petersburg Daiichi Sankyo ยท Tests: Quizartinib Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment NCT07422610Phase 110 sites๐Ÿ“ Bordeaux๐Ÿ“ Saint-Herblain๐Ÿ“ Milan Novartis Pharmaceuticals ยท Tests: pelabresib Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations NCT07654855n/a6 sites๐Ÿ“ Los Angeles๐Ÿ“ Vancouver๐Ÿ“ Beijing AstraZeneca ยท Tests: None ( observational study ) Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment NCT04617522Phase 115 sites๐Ÿ“ Long Beach๐Ÿ“ Newark๐Ÿ“ Baltimore Gilead Sciences ยท Tests: Sacituzumab Govitecan-hziy A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment NCT07165002Phase 13 sites๐Ÿ“ Kistarcsa๐Ÿ“ Auckland๐Ÿ“ Bratislava Eli Lilly and Company ยท Tests: LY3537031 A Study to Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function NCT07231991Phase 14 sites๐Ÿ“ Miami๐Ÿ“ Miami Lakes๐Ÿ“ Orlando Pfizer ยท Tests: vepdegestrant A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine NCT06682988Phase 252 sites๐Ÿ“ Sarasota๐Ÿ“ Edgewood๐Ÿ“ Lexington AbbVie ยท Tests: Mirvetuximab Soravtansine A Pharmacokinetic Study of TS-172 in Patients With Hepatic Impairment NCT07231029Phase 11 site๐Ÿ“ Tokyo Taisho Pharmaceutical Co., Ltd. ยท Tests: TS-172 A Trial to Examine if Repinatrabit is Processed Differently in Adults With Reduced Liver or Kidney Function Compared to Adults With Normal Liver and Kidney Function NCT07713758Phase 11 site๐Ÿ“ Miami Otsuka Pharmaceutical Development & Commercialization, Inc. ยท Tests: Repinatrabit A Study of HDM1002 in Subjects With And Without Varying Degrees Of Hepatic Impairement NCT06985615Phase 11 site๐Ÿ“ Suzhou Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. ยท Tests: Single dose of HDM1002 on Day 1 Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib NCT06997276Phase 13 sites๐Ÿ“ Miami๐Ÿ“ Orlando๐Ÿ“ San Antonio SpringWorks Therapeutics, Inc., a healthcare company of Merโ€ฆ ยท Tests: Mirdametinib (MEK Inhibitor) A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of HS-10506 NCT07844967Phase 11 site๐Ÿ“ Hefei Jiangsu Hansoh Pharmaceutical Co., Ltd. ยท Tests: HS-10506 Pharmacokinetic Study of Vorolanib Tablets in Trial Participants With Hepatic Impairment NCT07809802Phase 11 site๐Ÿ“ Changchun Betta Pharmaceuticals Co., Ltd. ยท Tests: vorolanib, vorolanib, Vorolanib Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HSK39297 in Subjects With Hepatic Impairment NCT07152288Phase 11 site๐Ÿ“ Beijing Haisco Pharmaceutical Group Co., Ltd. ยท Tests: HSK39297 tablets, HSK39297 tablets, HSK39297 tablets Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment NCT04953910Phase 122 sites๐Ÿ“ Houston๐Ÿ“ Yerevan๐Ÿ“ Yerevan Taiho Oncology, Inc. ยท Tests: ASTX727 A Study to Evaluate the Pharmacokinetics (PK) and Safety of a Single Dose of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Normal Hepatic Function and Participants With Hepatic Impairment NCT07643155Phase 14 sites๐Ÿ“ Lake Forest๐Ÿ“ San Dimas๐Ÿ“ Orlando Insmed Incorporated ยท Tests: Treprostinil Palmitil Inhalation Powder
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