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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Hypercholesterolaemia

Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH) NCT07447648n/a13 sites📍 Paris📍 Caserta📍 Catania Fondazione SISA (Societa Italiana per lo Studio della Arter… A Study to Compare PK Characteristics and Safety Profiles Between AD-228B and AD-2284 NCT06884098Phase 11 site📍 Seoul Addpharma Inc. · Tests: AD-228B, AD-2284 The ORIGIN-FH Study NCT07470723NA1 site📍 Madison University of Wisconsin, Madison · Tests: Screening for FH Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis NCT07307989Phase 21 site📍 Pozi Chang Gung Memorial Hospital · Tests: statin + ezetimibe, Statin monotherapy (rosuvastatin or atorvastatin) A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia NCT07206472n/a38 sites📍 Belo Horizonte📍 Belo Horizonte📍 Belo Horizonte Daiichi Sankyo · Tests: Combination of bempedoic acid and ezetimibe Study of the Determinants of Coronary Atherosclerosis in Familial Hypercholesterolemia (ATHERO-FH Study) NCT06960902NA9 sites📍 Dijon📍 Lille📍 Lyon Nantes University Hospital · Tests: Coronary CT scan with CAC score measurement Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention NCT06909565Phase 4147 sites📍 Alexander City📍 Birmingham📍 Huntsville Duke University · Tests: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL, Normal Saline (Placebo) Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers NCT06422741NA2 sites📍 Reus📍 Reus Fundació Eurecat · Tests: grape seed proanthocyanidin extract, Placebo Child-Parent Familial Hypercholesterolemia Screening NCT04529967n/a6 sites📍 Hefei📍 Qidong📍 Shanghai Children's Hospital of Fudan University · Tests: no interventions Multicomponent Intervention Study- Blood Donors With High Cholesterol NCT05693701NA1 site📍 Dallas University of Texas Southwestern Medical Center · Tests: Implementation Strategy Bundle, Usual care notification A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia NCT06568471Phase 318 sites📍 Beijing📍 Beijing📍 Beijing Hasten Biopharmaceutical Co., Ltd. · Tests: Lerodalcibep, matching placebo Phase II Clinical Trial to Evaluate the Efficacy and Safety of SYH2070 Injection in Participants With Homozygous Familial Hypercholesterolemia NCT07591298Phase 21 site📍 Changsha CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · Tests: SYH2070 injection dose1, SYH2070 injection dose2 Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia NCT06597019Phase 366 sites📍 San Francisco📍 San Francisco📍 Washington D.C. Novartis Pharmaceuticals · Tests: Inclisiran, Placebo Pharmacogenomic Informed Statin Prescribing NCT06568601NA2 sites📍 Indianapolis📍 Durham VA Office of Research and Development · Tests: Pharmacogenetic and polygenic risk testing, Active control Mechanism of Ketogenic Diet-Induced Hypercholesterolemia NCT06894004NA1 site📍 St Louis Washington University School of Medicine · Tests: Ketogenic Diet, Control Diet 2-Hydroxybenzylamine (2-HOBA) to Reduce HDL Modification and Improve HDL Function in Familial Hypercholesterolemia (FH) NCT04941599Phase 21 site📍 Nashville Vanderbilt University Medical Center · Tests: 2-Hydroxybenzylamine, Placebo Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia NCT07295327NA1 site📍 Pavia Fondazione IRCCS Policlinico San Matteo di Pavia · Tests: Cynacol, Metacol Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids NCT04485871NA1 site📍 Montreal Institut de Recherches Cliniques de Montreal · Tests: Omega-3 fatty acids Alirocumab in Patients on a Stable Dialysis Regimen NCT03480568Phase 31 site📍 Dallas Baylor Research Institute · Tests: Alirocumab 150 MG/ML [Praluent] A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia NCT07610278Phase 229 sites📍 Foley📍 Saraland📍 Lincoln Novartis Pharmaceuticals · Tests: QCZ484, Inclisiran, QCZ484 placebo, Inclisiran placebo LATAM LOWERS LDL-C NCT06501443Phase 411 sites📍 Corrientes📍 Salvador📍 Belo Horizonte Novartis Pharmaceuticals · Tests: Usual care, KJX839 Evaluation of Adherence, Persistence and Efficacy of Treatment With Alirocumab 300mg in Italy NCT07375225n/a1 site📍 Naples Federico II University · Tests: Praluent (Alirocumab) A Study to Evaluate the SYH2053 Injection in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) NCT07465263Phase 31 site📍 Beijing CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · Tests: SYH2053 Injection, Placebo Injection National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry NCT06546137n/a27 sites📍 Rio Branco📍 Maceió📍 Macapá Hospital do Coracao · Tests: whole genome sequencing Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea) NCT06770543n/a4 sites📍 Yangsan📍 Busan📍 Seoul Novartis Pharmaceuticals · Tests: Inclisiran Atlantic Lipid Lowering Treatment Optimization Program NCT06439654NA2 sites📍 Clark📍 Springfield Atlantic Health System · Tests: Supportive care A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias NCT07491172Phase 117 sites📍 Hialeah📍 Jacksonville📍 Orlando CRISPR Therapeutics AG · Tests: CTX310 High Intensity Interval Training in the Treatment of Familial Hypercholesterolemia (UPPA-FH) NCT06833944NA1 site📍 Granada Fundación Pública Andaluza para la Investigación Biomédica … · Tests: HIIT intervention program, MICT intervention program FELLAShip to Better Health NCT07220213NA1 site📍 Birmingham University of Alabama at Birmingham · Tests: FELLAship Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food NCT06988462NA1 site📍 Sommerville Cambridge Health Alliance · Tests: Bottarga, Comparator
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