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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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18 recruiting trials

for Langerhan's Cell Histiocytosis

Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study NCT04665674n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Standard of care Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites📍 Scottsdale📍 Rochester Mayo Clinic · Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone Lesions NCT07371182NA11 sites📍 Hefei📍 Nanning📍 Guiyang West China Second University Hospital · Tests: Luvometinib Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH NCT07187193Phase 21 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Cytarabine (Ara-C), Thalidomide (100mg) Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children NCT07022834Phase 21 site📍 Chengdu West China Second University Hospital · Tests: Dabrafenib or Trametinib and Clofarabine Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses NCT03329274n/a1 site📍 New York Memorial Sloan Kettering Cancer Center Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence NCT06078969Phase 21 site📍 Shanghai Shanghai Changzheng Hospital · Tests: Prednisone Mirdametinib in Histiocytic Disorders NCT06153173Phase 21 site📍 Cincinnati Children's Hospital Medical Center, Cincinnati · Tests: Mirdametinib Project: Every Child for Younger Patients With Cancer NCT02402244n/a279 sites📍 Birmingham📍 Mobile📍 Anchorage Children's Oncology Group · Tests: Cytology Specimen Collection Procedure, Medical Chart Review Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders NCT04079179Phase 212 sites📍 Phoenix📍 Little Rock📍 Orange Carl Allen · Tests: Cobimetinib DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. NCT07440290Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Dabrafenib, Trametinib A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis NCT05828069Phase 2121 sites📍 Birmingham📍 Little Rock📍 Downey National Cancer Institute (NCI) · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Echocardiography Test Histiocytic Disorder Follow-up Study NCT05915208n/a1 site📍 Birmingham University of Alabama at Birmingham Biomarkers for Diagnostic, Prognostic and of Response to Treatment in Adult Langerhans Cell Histiocytosis NCT06197204n/a1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Blood sampling, Biopsy, Blood sampling Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH) NCT02670707Phase 311 sites📍 Palo Alto📍 San Diego📍 Minneapolis Baylor College of Medicine · Tests: Cytarabine, Vinblastine/prednisone Modified LCH-III Regimen With or Without Luvometinib for Multisystem Pediatric Langerhans Cell Histiocytosis NCT07431060NA11 sites📍 Chengdu📍 Guiyang📍 Hefei West China Second University Hospital · Tests: Prednisone, Vincristine, Mercaptopurine, Luvometinib Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib NCT06582745Phase 21 site📍 Fort Worth Cook Children's Health Care System · Tests: Trametinib To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH NCT05997602Phase 211 sites📍 Beijing📍 Beijing📍 Chongqing Shanghai Fosun Pharmaceutical Industrial Development Co. Lt… · Tests: FCN-159
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