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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Left Atrial Appendage Closure

Can Patients With Atrial Fibrillation Safely Discontinue Anticoagulant Therapy After Cardiac Surgery? (ATLAAC) NCT06401616Phase 46 sites📍 Copenhagen📍 Gentofte Municipality📍 Herning Odense University Hospital · Tests: OAC will be discontinued for the duration of the trial Catheter Ablation Plus LAAO Versus Anticoagulation in Frail Elderly Patients With Atrial Fibrillation NCT07441382NA1 site📍 Guangzhou Guangdong Provincial People's Hospital · Tests: catheter ablation combined with LAAO (Left Atrial Appendage Occlusion), Atrial Fibrillation Radiofrequency Ablation Only CLOT-LESS - CLOsure Tailored: LEss Antithrombotic Strategy After LAAC for Stroke Prevention NCT07575867n/a1 site📍 Moscow National Medical Research Center for Therapy and Preventive… · Tests: Left Atrial Appendage Closure, Apixaban 2.5 mg BID, Standard-dose DOAC Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding. NCT04298723NA39 sites📍 Mannheim📍 Bad Neustadt an der Saale📍 Burgau Jena University Hospital · Tests: Percutaneous closure of the LAA (Watchman / Watchman FLX) Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion NCT06348394NA1 site📍 Plano Baylor Research Institute · Tests: Intracardiac Echocardiography, Traditional transesophageal echocardiography COCONUT Study Concomitant PVI and LAAC NCT06861673n/a1 site📍 Hamburg Asklepios proresearch · Tests: Pulmonary vein isolation Optimal Antiplatelet Therapy Following Left Atrial Appendage Closure NCT03445949Phase 41 site📍 Warsaw National Institute of Cardiology, Warsaw, Poland · Tests: short postimplantation dual antiplatelet therapy, extended postimplantation dual antiplatelet therapy, long-term treatm… Comparison of the Amplatzer Amulet Versus LAmbre Device for Left Atrial Appendage Closure NCT07260474NA1 site📍 Fuencarral-El Pardo Fundación EPIC · Tests: Patients implanted with Amplatzer Amulet™, Patients implanted with LAmbre™ Austrian Left Atrial Appendage Closure Registry NCT03409159n/a1 site📍 Graz Medical University of Graz · Tests: LAAC Agilis RF TSP Early Feasibility Study NCT07361445NA3 sites📍 Jonesboro📍 San Francisco📍 Kansas City Abbott Medical Devices · Tests: Transseptal procedure with Agilis RF TSP System. Zenith LAA Occlusion System NCT05951101NA3 sites📍 Parkville📍 Auckland📍 Christchurch AuriGen Medical Ltd · Tests: Zenith LAA Occlusion System Atrial Fibrillation TRIal of Left Atrial Appendage Closure Using Seralene Hemostatic Suture NCT07360899NA1 site📍 Kamenitz Institute of Cardiovascular Diseases, Vojvodina · Tests: LAA closure using the AtriLASH Left Atrial Appendage Closure in Patients With Non-valvular Atrial Fibrillation and End-stage Chronic KIDNEY Disease NCT05204212NA1 site📍 Lübeck Prof. Dr. med. Ingo Eitel · Tests: Left Atrial Appendage closure Study of the Effects of Anticoagulant Interruption Covered by Percutaneous Left Atrial Occlusion in Patients With Chronic Atrial Fibrillation and Radiation Cystitis at Risk of Bleeding NCT04701749n/a1 site📍 Clermont-Ferrand University Hospital, Clermont-Ferrand · Tests: Percutaneous left atrial closure, No Percutaneous left atrial closure Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion NCT06455644NA5 sites📍 Foshan📍 Foshan📍 Meizhou First Affiliated Hospital of Shantou University Medical Col… · Tests: CT group, DSA group The Role of Multimodality Imaging in Left Atrial Appendage Closure NCT04800913NA1 site📍 Budapest Hungarian Institute of Cardiology · Tests: Multimodal imaging, Standard imaging Safety and Effectiveness of Short-Term Single AntiPlatelet Therapy After Left Atrial Appendage Closure With the LAmbre Device in Patients With Nonvalvular Atrial Fibrillation: A Multinational Real-world Registry NCT06620757n/a22 sites📍 A Coruña📍 Aravaca📍 Barcelona Fundación EPIC · Tests: Single antiplatelet therapy (SAPT) The Impact of Atrial Pressure Change Before and After Combined Procedure NCT05106270n/a1 site📍 Shanghai Shanghai 10th People's Hospital · Tests: Atrial pressure measurement using transseptal puncture sheath Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry NCT06075628n/a1 site📍 Overland Park Kansas City Heart Rhythm Research Foundation · Tests: Left Atrial Appendage Occlusion Frailty in Patient Undergoing Percutaneous Left Atrial Appendage Closure. NCT05257954n/a1 site📍 Québec Josep Rodes-Cabau Safety and Performance of ENDOMATIC SEPIOLA Left Atrial Appendage (LAA) Closure Device NCT06099106NA5 sites📍 Tbilisi📍 Tbilisi📍 Vilnius Endomatic Ltd. · Tests: SEPIOLA System LAAC-registry: Clinical Outcome After Echocardiography-guided LAA-closure NCT04628078n/a1 site📍 Bern Insel Gruppe AG, University Hospital Bern · Tests: Use of echocardiography guidance for LAAC Left Atrial Appendage Closure as Secondary Prevention of Atrial Fibrillation-related Embolic Events NCT04559243n/a5 sites📍 Jinan📍 Shanghai📍 Mianyang Lifetech Scientific (Shenzhen) Co., Ltd. · Tests: Transthoracic Echocardiography Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy NCT05976685NA33 sites📍 Bruges📍 Brussels📍 Brussels Insel Gruppe AG, University Hospital Bern · Tests: Left atrial appendage Occlusion, DOAC Left Atrial Appendage Closure Registry of Henri Mondor Hospital NCT05565209n/a1 site📍 Créteil Assistance Publique - Hôpitaux de Paris · Tests: SA brief descriptive name used to refer to the intervention(s) studied OPTION-EMEA Clinical Trial NCT07349121NA11 sites📍 Aalst📍 Brussels📍 Zagreb Boston Scientific Corporation · Tests: Concomitant pulsed field ablation (PFA) and left atrial appendage closure (LAAC) during one interventional case, Concom… The Safety and Efficacy of Radiofrequency Ablation After Left Atrial Appendage Occlusion. NCT06984731n/a1 site📍 Nantong Affiliated Hospital of Nantong University · Tests: left atrial appendage closure, radiofrequency ablation Non-antithrombotic Versus. Single Antiplatelet Therapy Following Left Atrial Appendage Closure NCT07125417Phase 421 sites📍 Nagoya📍 Toyohashi📍 Matsudo OCEAN-SHD Study Group · Tests: Single Antiplatelet Therapy or No Therapy (Control), Non-Antithrombotic Therapy Oral Anticoagulation Versus Left Atrial Appendage Occlusion Added to Direct Oral Anticoagulation in Patients with Stroke Despite Oral NCT06869811NA1 site📍 Barcelona Hospital Clinic of Barcelona · Tests: LAA Closurse Elite AF IDE Trial (Elite AF) NCT07287436NA2 sites📍 Jonesboro📍 Charlotte Boston Scientific Corporation · Tests: WATCHMAN Elite LAAC Device
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