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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Leiomyosarcoma

Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma NCT07169344Phase 24 sites๐Ÿ“ Bergen๐Ÿ“ Oslo๐Ÿ“ Tromsรธ Oslo University Hospital ยท Tests: preoperative, Quality of life, Functional outcome A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy NCT07633756Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: REC617 Letrozole in Uterine Leiomyosarcoma NCT05649956Phase 234 sites๐Ÿ“ Aurora๐Ÿ“ Highlands Ranch๐Ÿ“ Fort Lauderdale GOG Foundation ยท Tests: Letrozole Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour NCT06524583Phase 225 sites๐Ÿ“ Angers๐Ÿ“ Besanรงon๐Ÿ“ Bordeaux UNICANCER ยท Tests: Doxorubicin, Trabectedin MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue Sarcoma NCT06277154Phase 21 site๐Ÿ“ Guangzhou HRYZ Biotech Co. ยท Tests: MASCT-I, Doxorubicin, Ifosfamide Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma NCT06528769Phase 21 site๐Ÿ“ Columbus Gabriel Tinoco ยท Tests: all-trans retinoic acid, Cemiplimab, Computed Tomography, Magnetic resonance imaging, Biospecimen Collection Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy NCT06170177n/a1 site๐Ÿ“ Milan IRCCS San Raffaele ยท Tests: Radical Cystectomy IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) NCT06849986Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Tislelizumab+liposomal doxorubicin+ifosfamide Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma NCT04535271Phase 21 site๐Ÿ“ Santa Monica Sarcoma Oncology Research Center, LLC ยท Tests: Trabectedin NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) NCT06239272Phase 1, Phase 27 sites๐Ÿ“ Atlanta๐Ÿ“ Chicago๐Ÿ“ Baton Rouge St. Jude Children's Research Hospital ยท Tests: Surgical resection, Proton beam radiation therapy, Pazopanib, Ifosfamide, Doxorubicin Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors NCT07628634EARLY Phase 11 site๐Ÿ“ Orange University of California, Irvine ยท Tests: Methionine-Reduced Diet Trial in Patients With Metastatic or Locally Advanced Leiomyosarcoma NCT04383119Phase 217 sites๐Ÿ“ Bologna๐Ÿ“ Meldola๐Ÿ“ Prato Italian Sarcoma Group ยท Tests: Trabectedin, Gemcitabine, No Intervention: Observational Cohort Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas NCT04055220NA16 sites๐Ÿ“ Besanรงon๐Ÿ“ Bordeaux๐Ÿ“ Lille Centre Leon Berard ยท Tests: Treatment by Regorafenib, Surveillance Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a2 sites๐Ÿ“ Sioux Falls๐Ÿ“ Sydney Sanford Health Localized Leiomyosarcoma Biomarker Protocol NCT04925089n/a3 sites๐Ÿ“ Ann Arbor๐Ÿ“ Rochester๐Ÿ“ Nashville University of Michigan Rogel Cancer Center ยท Tests: Blood and Tissue collection Zanzalintinib Combined With Eribulin in Advanced Liposarcoma and Leiomyosarcoma NCT06957431Phase 11 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: Zanzalintinib, Eribulin Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) NCT03016819Phase 324 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Santa Monica Advenchen Laboratories, LLC ยท Tests: AL3818, Dacarbazine, AL3818 or placebo, Midazolam 2 mg for CYP3A4 phenotyping, Digoxin (0.25mg) Metastatic Leiomyosarcoma Biomarker Protocol NCT05653388n/a11 sites๐Ÿ“ Santa Monica๐Ÿ“ Miami๐Ÿ“ Boston University of Michigan Rogel Cancer Center ยท Tests: Plasma Collection AOH1996 for the Treatment of Refractory Solid Tumors NCT05227326Phase 13 sites๐Ÿ“ Scottsdale๐Ÿ“ Duarte๐Ÿ“ Long Beach City of Hope Medical Center ยท Tests: PCNA Inhibitor AOH1996 Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma. NCT07173972Phase 22 sites๐Ÿ“ Bergen๐Ÿ“ Oslo Oslo University Hospital ยท Tests: Definitive radiotherapy A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers NCT06541652n/a40 sites๐Ÿ“ Amiens๐Ÿ“ Angers๐Ÿ“ Beauvais Federation Francophone de Cancerologie Digestive Ph 2 Elacestrant in ER Positive Uterine Sarcomas NCT07467772Phase 21 site๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Elacestrant Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients NCT02275286Phase 1, Phase 217 sites๐Ÿ“ Bordeaux๐Ÿ“ Lyon๐Ÿ“ Rozzano Grupo Espanol de Investigacion en Sarcomas ยท Tests: Trabectedin, Radiotherapy Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS NCT07076186Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Trabectedin, Doxorubicin Hydrochloride XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma NCT06571734Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Echocardiography, Multigated Acquisition Scan, Zanzalintinib A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors NCT06789172Phase 110 sites๐Ÿ“ Beverly Hills๐Ÿ“ Santa Monica๐Ÿ“ Houston Epkin ยท Tests: OKN4395, Pembrolizumab, Fasting, Fed, H2 Receptor Antagonist STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas NCT06975293Phase 1, Phase 214 sites๐Ÿ“ San Francisco๐Ÿ“ Miami๐Ÿ“ Boston STORM Therapeutics LTD ยท Tests: STC-15 in combination with toripalimab, STC-15 monotherapy Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma NCT06498648Phase 1, Phase 21 site๐Ÿ“ Houston National Cancer Institute (NCI) ยท Tests: Abemaciclib, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Docetaxel Beliefs, Attitudes, and Response to Genetic Testing in SarcomaPatients NCT06875700n/a1 site๐Ÿ“ Salt Lake City University of Utah Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients NCT07432932n/a1 site๐Ÿ“ London Royal Marsden NHS Foundation Trust ยท Tests: Observational Translational Study
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