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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Light Chain (AL) Amyloidosis

SMS-Based Remote Symptom Monitoring for Patients With Plasma Cell Disorders NCT07850284n/a1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Non-Interventional Study A Phase II Study to Evaluate the Efficacy and Safety of Teclistamab in Combination With Daratumumab (Tec-Dara) in Newly Diagnosed Multiple Myeloma With Concurrent Light Chain Amyloidosis (MM+AL). NCT07638683Phase 21 site๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Teclistamab Prospective Study of Teclistamab in the Treatment of Systemic AL Amyloidosis NCT06699394NA2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Teclistamab (Tec) Promoting Diagnosis and Management of AL in Italy (ProDigALIty) NCT06383143n/a4 sites๐Ÿ“ Bari๐Ÿ“ Catania๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia ยท Tests: no intervention Rapid dFLC Response Predict CHR in AL Amyloidosis NCT06627309n/a8 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: Dara IV, Bortezomib (drug), Dexamethasone, Cyclophosphamide (CTX), Dara SC Screening for AL Amyloidosis in Smoldering Multiple Myeloma NCT06365060n/a13 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Tufts Medical Center Daratumumab for Patients With Light Chain Amyloidosis NCT06376214NA1 site๐Ÿ“ Nanjing Nanjing University School of Medicine ยท Tests: Dratumumab / Hyaluronidase Injection [Darzalex Faspro], Pomalidomide 4 MG, autologous stem cell transplantation (ASCT) A Registry of AL Amyloidosis (ReAL) NCT04839003n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Bortezomib, Pomalidomide, Dexamethasone for Systemic AL Amyloidosis NCT06342466Phase 21 site๐Ÿ“ Beijing Jin Lu, MD ยท Tests: Bortezomib, Pomalidomide, Dexamethasone A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis NCT05652335Phase 129 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ San Francisco Janssen Research & Development, LLC ยท Tests: JNJ-79635322 The Norwegian Immunotherapy in Multiple Myeloma Study NCT06855121n/a23 sites๐Ÿ“ Arendal๐Ÿ“ ร…lesund๐Ÿ“ Bergen St. Olavs Hospital ยท Tests: Teclistamab, Elranatamab, Ciltacabtagene Autoleucel, Talquetamab, Idecabtagene vicleucel Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis NCT07250269Phase 19 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Gracell Biotechnologies (Shanghai) Co., Ltd. ยท Tests: GC012F Injection Hungarian National Systemic Amyloidosis Registry NCT07689331n/a12 sites๐Ÿ“ Balatonfรผred๐Ÿ“ Budapest๐Ÿ“ Budapest Semmelweis University A EUropean REgistry and Sample Sharing networK to Promote the Diagnosis and Management of Light Chain Amyloidosis (EUREKA) NCT06205953n/a6 sites๐Ÿ“ Heidelberg๐Ÿ“ Pavia๐Ÿ“ Utrecht Fondazione IRCCS Policlinico San Matteo di Pavia Evaluation of Skin Tests in Biotherapy Allergies NCT06971848NA1 site๐Ÿ“ Angers University Hospital, Angers ยท Tests: Drug skin tests (investigating hypersensitivity to a biotherapy) Investigating the Pathogenic Role of N-glycosylation in AL Amyloidosis: Molecular Bases, Diagnosis, and Treatment NCT07448779n/a1 site๐Ÿ“ Pavia Fondazione IRCCS Policlinico San Matteo di Pavia A Phase 1 Study of 99mTc-p5+14 in Healthy Volunteers and Patients With AL or ATTR Systemic Amyloidosis NCT05951816Phase 11 site๐Ÿ“ Knoxville University of Tennessee Graduate School of Medicine ยท Tests: 99mTc-p5+14 is an amyloid reactive peptide labeled with technetium-99m., 99mTc-Pyrophosphate Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research NCT07085559EARLY Phase 11 site๐Ÿ“ Hefei Anhui Provincial Hospital ยท Tests: Metabolically Armed BCMA CAR-T cells. Beta-amyloid PET/CT to Measure Potential Therapeutic Response in AL-CA NCT07829705Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: 11C-PIB, 18F-Florbetapir Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis NCT06022939Phase 3117 sites๐Ÿ“ Goodyear๐Ÿ“ Tucson๐Ÿ“ Tucson SWOG Cancer Research Network ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrowโ€ฆ Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis NCT07335887Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Xi'an Peking University People's Hospital ยท Tests: sonrotoclax, Daratumumab, Dexamethasone Teclistamab in Previously Treated AL Amyloidosis NCT06935162Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Teclistamab (Tec) BE.Amycon Biobank & Data Registry UZ Leuven NCT07172243n/a2 sites๐Ÿ“ Leuven๐Ÿ“ Leuven Universitaire Ziekenhuizen KU Leuven A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma NCT06768489Phase 116 sites๐Ÿ“ Denver๐Ÿ“ Atlanta๐Ÿ“ Clayton Janssen Research & Development, LLC ยท Tests: JNJ-79635322, Daratumumab, Pomalidomide, Lenalidomide A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis NCT07224672Phase 25 sites๐Ÿ“ Rochester๐Ÿ“ Westmead๐Ÿ“ Woolloongabba GlaxoSmithKline ยท Tests: Belantamab mafodotin, Cyclophosphamide, Bortezomib, Dexamethasone Teclistamab-Daratumumab in AL Amyloidosis NCT07110844Phase 23 sites๐Ÿ“ Boston๐Ÿ“ New York๐Ÿ“ Milwaukee Rajshekhar Chakraborty, MD ยท Tests: Teclistamab, Daratumumab and Hyaluronidase-fihj A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis. NCT07081646Phase 1, Phase 218 sites๐Ÿ“ Phoenix๐Ÿ“ San Francisco๐Ÿ“ Tampa Alexion Pharmaceuticals, Inc. ยท Tests: AZD0120 Clinical Study for AL-CM NCT04924998n/a1 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: current treatment of AL-CM Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource NCT01408225n/a1 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: tissue banking Elranatamab in Patients With Relapsed or Refractory AL Amyloidosis NCT06569147Phase 1, Phase 25 sites๐Ÿ“ New Haven๐Ÿ“ Boston๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Elranatamab
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