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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Local Neoplasm Recurrence

Additional Treatment for Isolated Local Pancreatic Cancer Recurrence Using Stereotactic Body Radiation Therapy NCT04881487NA3 sites📍 Amsterdam📍 Rotterdam📍 Utrecht UMC Utrecht · Tests: Additional stereotactic body radiation therapy Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer NCT06307548Phase 1, Phase 21 site📍 Buffalo Roswell Park Cancer Institute · Tests: Aminolevulinic Acid, Biospecimen Collection, Computed Tomography, Fluorescence-Guided Surgery, Magnetic Resonance Imagi… Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer NCT05933889n/a1 site📍 London Royal Marsden NHS Foundation Trust · Tests: Molecular Analysis, Radiomic/ Morphological analysis MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC NCT07331428Phase 21 site📍 Fuzhou Fujian Cancer Hospital · Tests: MRG003, Tislelizumab, Capecitabine High Dose Rate (HDR) Brachytherapy Salvage After Prostatectomy NCT06982469n/a1 site📍 Pamplona Clinica Universidad de Navarra, Universidad de Navarra · Tests: Brachytherapy Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDG… Study Comparing Different Neck Treatment Approaches in Patients With Oral Cancer Without Visible Neck Spread NCT07726199NA1 site📍 Kolhāpur Kolhapur Cancer Centre - Cancer Centers of America · Tests: Selective Neck Dissection (Levels I-IV), Intervention : Selective Neck Dissection (Levels I-III) Salvage HDR for Locally Recurrent Prostate Cancer NCT04231006NA1 site📍 Aarhus Aarhus University Hospital · Tests: High dose rate brachytherapy Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells NCT06302465NA1 site📍 Beijing Peking University People's Hospital · Tests: narlumosbartmab plus doxorubicin、cisplatin、methotrexate、ifosfamide, doxorubicin、cisplatin、methotrexate、ifosfamide TN Induction and Adjuvant Therapy for Resectable Local Recurrent Nasopharyngeal Carcinoma NCT06912711Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Toripalimab, Nimotuzumab, surgery The Comparison of TACE-Lenvatinib With TACE-Lenvatinib-ablation for Intermediate Recurrent Hepatocellular Carcinoma NCT06609850NA1 site📍 Beijing Sun Yat-sen University · Tests: TACE, Ablation, Lenvatinb Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging NCT04423211Phase 3341 sites📍 Anchorage📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography, Degarelix, External Beam Radiation Therapy A Phase1 Clinical Trial Evaluating Locoregional Delivery Of Engineered NK Cells Containing IL13Ra And EGFvIII Chimeric Antigen Receptor (CAR), IL-21 Secretion And Deleted TGF-BetaR2 And NR3C1 In Recurrent Glioblastoma NCT07579208Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: NK Cells, NK Cells Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image Guidance NCT07636148n/a3 sites📍 Lyon📍 Créteil📍 Leiden Mark C Burgmans, MD PhD Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone NCT03295981Phase 316 sites📍 Los Angeles📍 Indianapolis📍 Iowa City St. Louis University · Tests: Zoledronic Acid Chemoradiotherapy Plus Anti-PD1 in Recurrent NPC: A Multicenter, Open-label, Randomised, Controlled, Phase III Trial NCT05340491Phase 312 sites📍 Guangzhou📍 Beijing📍 Chengdu Sun Yat-sen University · Tests: Toripalimab, Chemotherapy, Intensity modulated radiotherapy Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells NCT04254419Phase 11 site📍 Columbus Nationwide Children's Hospital · Tests: NK cells Search for Circulating Tumour Cells in the Blood and/or Cerebrospinal Fluid in Patients With Recurrent Aggressive Meningiomas: Proof-of-concept Study NCT07398170NA1 site📍 Montpellier University Hospital, Montpellier · Tests: Blood sampling, Lumbar puncture WoW - Single- vs Two-staged Excisions of Thin Melanoma NCT06363591NA1 site📍 Gothenburg Vastra Gotaland Region · Tests: Surgery, No Surgery PD-1 Combined With Chemotherapy and PULSAR in LAPC and Local Recurrence Patients NCT06359275Phase 21 site📍 Shanhai Fudan University · Tests: PD-1, Nab-paclitaxel, Gemcitabine, PULSAR Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma NCT00107289Phase 21 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: iobenguane I 131 Combination of CAR-DC Vaccine and ICIs in Malignant Tumors NCT05631886Phase 11 site📍 Beijing Chinese PLA General Hospital · Tests: TP53-EphA-2-CAR-DC, Abraxane, Cyclophosphamide, anti-PD-1 antibody, Anti-CTLA4 Monoclonal Antibody Tris-CAR-T Cell Therapy for Recurrent Glioblastoma NCT05577091Phase 11 site📍 Beijing Beijing Tiantan Hospital · Tests: Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes. Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma NCT07551336Phase 11 site📍 Shenzhen Beijing Biotech · Tests: Dual-target CAR-NK cells, Cyclophosphamide, Intracranial catheter/reservoir for locoregional delivery, Fludarabine Study on Prostate Salvage Using High-dose-rate Brachytherapy NCT07860528n/a10 sites📍 Benidorm📍 L'Hospitalet de Llobregat📍 Santander Instituto de Investigación en Oncología Radioterápica - Fun… Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity and HPV-negative Oropharyngeal Squamous Cell Carcinoma NCT06448026Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Cemiplimab, Cetuximab A Translational Study for Locoregional Recurrence of T4 Colon Cancer NCT06958926n/a1 site📍 Hsinchu National Taiwan University Hospital · Tests: Radical surgery for colon and rectum cancer, Radical surgery for colorectal cancer Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma NCT07100730Phase 39 sites📍 Gold Coast📍 Melbourne📍 Perth Telix Pharmaceuticals (Innovations) Pty Limited · Tests: TLX-101-Tx + Lomustine, TLX101-Tx Personalization of Breast Radiotherapy According to Loco-regional Recurrence Risk and Toxicity Probability NCT06382818NA1 site📍 Montpellier Institut du Cancer de Montpellier - Val d'Aurelle · Tests: COHORT A, COHORT B, COHORT C, COHORT D
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