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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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25 recruiting trials

for Locally Advanced or Metastatic Melanoma

To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma NCT06204991Phase 12 sites๐Ÿ“ Herlev๐Ÿ“ Herlev Inge Marie Svane ยท Tests: ADP-TILIL7, Cyclophosphamide, Fludarabine Phosphate, Proleukin Anti PD-1 Plus Postbiotic Versus Anti PD-1 Alone in Locally Advanced or Metastatic, Treatment naรฏve, Cutaneous Melanoma Study NCT07050940NA5 sites๐Ÿ“ Bari๐Ÿ“ Torino๐Ÿ“ Bari Azienda Ospedaliera di Perugia ยท Tests: Postbiotic, AntiPD1 Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib A Study to Evaluate the Efficacy and Safety of IBI363 Monotherapy Compared to Pembrolizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal or Acral Melanoma Who Had Not Previously Received Systemic Therapy NCT06797297Phase 231 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI363, Pembrolizumab EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ยฑ Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: EBNK-001 + IL-15 + Pembrolizumab A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) Opdualag vs. Cemiplimab/Fianlimab in Relation to the Immunological Response in Tumor and Peripheral Blood in Unresectable or Metastatic Melanoma NCT07223411n/a1 site๐Ÿ“ Pittsburgh John Kirkwood ยท Tests: Fianlimab + Cemiplimab, Relatlimab + Nivolumab Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors NCT05970497Phase 1, Phase 215 sites๐Ÿ“ Los Angeles๐Ÿ“ Rancho Santa Margarita๐Ÿ“ Weston Krystal Biotech, Inc. ยท Tests: KB707, Opdualag, KEYTRUDA ยฎ( Pembrolizumab) A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body NCT06413680Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ North Haven Regeneron Pharmaceuticals ยท Tests: REGN10597, Cemiplimab Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer NCT05098210Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Neoantigen Peptide Vaccine, Nivolumab, Poly ICLC, Echocardiography Test, Multigated Acquisition Scan Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab AB821 in Adult Participants With Locally Advanced or Metastatic Solid Tumors NCT07027488Phase 11 site๐Ÿ“ New Haven Yale University ยท Tests: AB821 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment NCT04045691n/a59 sites๐Ÿ“ Graz๐Ÿ“ Innsbruck๐Ÿ“ Klagenfurt Pierre Fabre Pharma GmbH ยท Tests: Encorafenib, Binimetinib Phase I/II Clinical Study of JMT108 Injection for the Treatment of Advanced Malignant Melanoma and Urinary Tract Tumors NCT07280832Phase 1, Phase 21 site๐Ÿ“ Beijing Shanghai JMT-Bio Inc. ยท Tests: JMT108 Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma NCT05498792EARLY Phase 11 site๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: CBL0137, Ipilimumab, Nivolumab BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Beverly Hills National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection Belvarafenib in Combination With Cobimetinib in Patients With Locally Advanced or Metastatic NRAS-Mutant Melanoma NCT07449754Phase 210 sites๐Ÿ“ Seongnam-si๐Ÿ“ Hwasun๐Ÿ“ Busan Hanmi Pharmaceutical Company Limited ยท Tests: Belvarafenib, Cobimetinib Study to Evaluate Impactยฎ as Support to Anti PD1 or Anti PD1 Based Regimen Treatment in Patients With Inoperable Locally Advanced or Metastatic Melanoma NCT06880198NA1 site๐Ÿ“ Naples Fondazione Melanoma Onlus ยท Tests: Oral Impactยฎ A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors NCT06880549Phase 14 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ San Antonio ModernaTX, Inc. ยท Tests: mRNA-4106, Pembrolizumab, mRNA-4200 A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors NCT06172478Phase 296 sites๐Ÿ“ Duarte๐Ÿ“ New Haven๐Ÿ“ Kissimmee Daiichi Sankyo ยท Tests: HER3-DXd GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul GeneMedicine Co., Ltd. ยท Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors NCT07410494Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: EB-SELECT Single-Target CAR-NK Cells, Dual-Target Antigen-Selected CAR-NK
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