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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Lung Cancer Stage IV

A Study to Evaluate Efficacy, and Safety of QL2107 Plus Chemo and Compare With Keytruda in Participants With IV nqNSCLC NCT06754644Phase 31 site📍 Jinan Qilu Pharmaceutical Co., Ltd. · Tests: QL2107, Pemetrexed, Carboplatin, Keytruda® Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC NCT06162221Phase 1, Phase 298 sites📍 Gilbert📍 Duarte📍 Irvine Revolution Medicines, Inc. · Tests: RMC-6291, RMC-6236, Pembrolizumab, Cisplatin, Carboplatin GT103 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic STK11 Mutant Non-Small Cell Lung Cancer NCT07017829Phase 21 site📍 Buffalo Roswell Park Cancer Institute · Tests: Anti-CFH Monoclonal Antibody GT103, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site📍 Chicago Northwestern University · Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation NCT07012031Phase 1, Phase 29 sites📍 Sacramento📍 Tampa📍 Tampa National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Characteristics of Advanced LUNG CANCER at the tIme of Diagnosis in a Large Italian Cohor NCT06076005n/a3 sites📍 Roma📍 Roma📍 Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: Advanced lung cancer patients' group Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer NCT06287775Phase 1, Phase 243 sites📍 Duarte📍 Irvine📍 La Jolla National Cancer Institute (NCI) · Tests: Atezolizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Durvalumab A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202) NCT05920356Phase 3424 sites📍 Santa Barbara📍 Newark📍 Coral Springs Amgen · Tests: Sotorasib, Pembrolizumab Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial) NCT06116682Phase 2271 sites📍 Jonesboro📍 Little Rock📍 Auburn SWOG Cancer Research Network · Tests: Amivantamab, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site📍 Portland OHSU Knight Cancer Institute · Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Avapritinib Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations NCT06772623Phase 1, Phase 2126 sites📍 Phoenix📍 Fullerton📍 Oxnard AbbVie · Tests: Telisotuzumab Adizutecan, Budigalimab, Pembrolizumab, Pembrolizumab, Carboplatin Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) NCT07149649Phase 2, Phase 311 sites📍 Aarau📍 Aarau📍 Baden Swiss Cancer Institute · Tests: Magnesiocard, Magnesium Diasporal, Microcrystalline cellulose, Isotonic saline solution 0.9% Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer NCT07250477Phase 24 sites📍 Chico📍 Marysville📍 Sacramento University of California, Davis · Tests: Systemic (ICI)-based therapy informed by the PROphet CB assay and the CARG-TT assessment., Standard of Care Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial NCT07288034Phase 213 sites📍 Goodyear📍 Corona📍 Duarte City of Hope Medical Center · Tests: Adagrasib, Anti-PD-L1 Monoclonal Antibody, Anti-PD1 Monoclonal Antibody, Bevacizumab, Biopsy Procedure Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient NCT07198217Phase 21 site📍 Zibo Zibo Municipal Hospital · Tests: SBRT combined with Tislelizumab followed by Tislelizumab Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer NCT05493566EARLY Phase 11 site📍 Atlanta Emory University · Tests: Aldesleukin, Pembrolizumab Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial NCT06500481Phase 358 sites📍 Phoenix📍 Little Rock📍 Encinitas NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Involved-Field Radiation Therapy, Lumbar Puncture, Magnetic Resonance Imag… Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers NCT05296564Phase 1, Phase 21 site📍 Jerusalem Hadassah Medical Organization · Tests: CYCLOPHOSPHAMIDE and FLUDARABIN, Cyclophosphamide, HBI 0201-ESO TCRT, Aldesleukin A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer NCT07155187Phase 2, Phase 3117 sites📍 Springdale📍 Duarte📍 Irvine AbbVie · Tests: Telisotuzumab Adizutecan, Standard of Care, Osimertinib Trial Comparing Systemic Therapy Alone and With Local Ablative Treatment for Stage IV NSCL Cancer Patients NCT06114108NA7 sites📍 Aarau📍 Bellinzona📍 Chur Swiss Cancer Institute · Tests: Systemic therapy alone or in combination with LAT (surgery and/or radiotherapy), Surgery, Radiotherapy A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer NCT06122064NA1 site📍 Rochester Mayo Clinic · Tests: Best Practice, Communication Intervention, Electronic Health Record Review, Survey Administration, Video Recording Osimertinib With or Without Primary Lung Tumor Resection for EGFR-Mutant Oligometastatic Non-Small Cell Lung Cancer NCT07738172Phase 31 site📍 Taipei National Taiwan University Hospital · Tests: Primary Tumor Resection, Osimertinib Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer NCT05501665Phase 1, Phase 21 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Biospecimen Collection, Carboplatin, Computed Tomography, Fludeoxyglucose F-18, Nab-paclitaxel Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy NCT03042221n/a1 site📍 Aurora University of Colorado, Denver A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01) NCT06780085Phase 235 sites📍 Lexington📍 Baltimore📍 Pittsburgh Merck Sharp & Dohme LLC · Tests: Raludotatug Deruxtecan, Ifinatamab Deruxtecan, Docetetaxel, 5-hydroxytryptamine subtype 3 receptor antagonist, Neurokin… Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases NCT06265350NA2 sites📍 Guanzhou📍 Guanzhou Sun Yat-sen University · Tests: Cadonilimab, Bevacizumab, Cryoablation Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer NCT05244239Phase 13 sites📍 Atlanta📍 Atlanta📍 Atlanta Emory University · Tests: Lurbinectedin, Palliative Radiation Therapy
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