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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Lupus Nephritis (LN)

A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1) NCT06557265Phase 1, Phase 219 sites๐Ÿ“ Little Rock๐Ÿ“ Tustin๐Ÿ“ Gainesville Nkarta, Inc. ยท Tests: NKX019, Fludarabine, Cyclophosphamide Assessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months of Intensified Treatment With Prednisolone, Mycofenolate Mofetil and Voclosporin as Compared to Mycofenolate Mofetil and Prednisolone NCT07760480Phase 41 site๐Ÿ“ Amsterdam Academisch Medisch Centrum - Universiteit van Amsterdam (AMโ€ฆ ยท Tests: Kidney Biopsy, Voclosporin (LUPKYNIS), Blood, feces and urine sample collection, LupusPRO questionnaire, Mycophenolate โ€ฆ A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis NCT07570862Phase 212 sites๐Ÿ“ Beverly Hills๐Ÿ“ Fontana๐Ÿ“ Fullerton Fate Therapeutics ยท Tests: FT819 The Efficacy and Safety of Biologics (Belimumab/ Telitacicept) Induction Therapy in Proliferative Lupus Nephritis Patients for 6 Months Compared With Mycophenolate Mofetil Treatment NCT07340463Phase 21 site๐Ÿ“ Nanjing Nanjing University School of Medicine ยท Tests: Glucocorticoids, belimumab, Telitacicept, Mycophenolate mofetil (MMF) Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN NCT06527872n/a7 sites๐Ÿ“ Baltimore๐Ÿ“ Charlotte๐Ÿ“ Columbus GlaxoSmithKline ยท Tests: None (Observational study) Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial) NCT07719140Phase 48 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing Peking Union Medical College Hospital ยท Tests: High-dose prednisone, Low-dose prednisone CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus NCT06839976Phase 1, Phase 21 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: CART19 Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders NCT06434363Phase 1, Phase 22 sites๐Ÿ“ Houston๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Tafasitamab, Fludarabine phosphate, Cyclophosphamide, Tafasitamab and NK cells A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis NCT07328581Phase 24 sites๐Ÿ“ Chicago๐Ÿ“ Hawthorne๐Ÿ“ New Hyde Park iCell Gene Therapeutics ยท Tests: ICG318, BCMA-CD19-IL-15/IL-15 sushi Compound CAR T following lymphodepletion CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH NCT06947460Phase 1, Phase 21 site๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: CD19-BCMA CAR-T cells infusion Lupus Nephritis Care Pathway NCT07783152NA1 site๐Ÿ“ Durham Duke University ยท Tests: Lupus Nephritis (LN) Care Pathway Study to Assess Efficacy and Safety of HSK39297 Tablets in Patients With LN NCT07363460Phase 21 site๐Ÿ“ Nanjing Haisco Pharmaceutical Group Co., Ltd. ยท Tests: HSK39297 200mgQD, HSK39297 300mgQD, Placebo Equecabtagene Autoleucel Injection (Eque-cel) for Relapsed/Refractory Systemic Lupus Erythematosus (SLE) NCT06902844NA1 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Equecabtagene Autoleucel Injection Dapagliflozin in Active Lupus Nephritis NCT07323524Phase 42 sites๐Ÿ“ Boston๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: Dapagliflozin (10Mg Tab) along with standard medical therapy, Placebo A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease NCT07085104Phase 117 sites๐Ÿ“ Phoenix๐Ÿ“ Loma Linda๐Ÿ“ Aurora Allogene Therapeutics ยท Tests: ALLO-329, Cyclophosphamide, Fludarabine A Study to Evaluate the Efficacy, Safety, and Tolerability of Human Sialidase Fusion Protein (HLX79) in Combination With Rituximab Injection Versus Placebo in Patients With Active Glomerulonephritis NCT07038382Phase 217 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Changsha Shanghai Henlius Biotech ยท Tests: HLX79 10mg/kg/Placebo+HLX01, HLX79 20mg/kg/Placebo + HLX01, HLX79 30mg/kg/placebo+HLX01 Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH. NCT06947473Phase 1, Phase 21 site๐Ÿ“ Beijing Beijing GoBroad Hospital ยท Tests: umbilical cord blood CD19-BCMA CAR-T cells infusion A Phase 1 Study of HB2198 in Participants With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) NCT07491900Phase 11 site๐Ÿ“ Brisbane Hinge Bio ยท Tests: HB2198 High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort) NCT06682507n/a1 site๐Ÿ“ Guangzhou First Affiliated Hospital, Sun Yat-Sen University ยท Tests: No Intervention: Observational Cohort Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN) NCT07053800Phase 215 sites๐Ÿ“ New York๐Ÿ“ Syracuse๐Ÿ“ San Antonio Autolus Limited ยท Tests: Obecabtagene autoleucel A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases NCT07123519Phase 11 site๐Ÿ“ Tianjin China Immunotech (Beijing) Biotechnology Co., Ltd. ยท Tests: YTS109 cell An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases NCT07236762Phase 11 site๐Ÿ“ Bengbu China Immunotech (Beijing) Biotechnology Co., Ltd. ยท Tests: YTS109 cell Biomarker Development for Autoimmune Disorders Involving the Kidneys NCT07666711n/a1 site๐Ÿ“ Oslo Oslo University Hospital ยท Tests: Longitudinal Blood and Urine Biomarker Monitoring Research Accelerated by You Lupus Registry NCT06927219n/a1 site๐Ÿ“ Washington D.C. Lupus Foundation of America Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension) NCT06711887Phase 351 sites๐Ÿ“ Orchard Park๐Ÿ“ Vitรณria๐Ÿ“ Salvador Novartis Pharmaceuticals ยท Tests: Ianalumab US Zamto-cel Autoimmune Diseases NCT06708845Phase 11 site๐Ÿ“ Milwaukee Miltenyi Biomedicine GmbH ยท Tests: zamtocabtagene autoleucel, Cyclophosphamide, Fludarabine Study to Evaluate the Safety and Preliminary Efficacy of CD19 CAR-T Cell Therapy (TranspoCART19) in Patients With Refractory Lupus Nephritis NCT07799116Phase 1, Phase 28 sites๐Ÿ“ Badalona๐Ÿ“ Santiago de Compostela๐Ÿ“ Pamplona Instituto de Investigaciรณn Sanitaria de la Fundaciรณn Jimรฉneโ€ฆ ยท Tests: TranspoCART19 Safety and Efficacy of ONT01 in Lupus NCT07107659EARLY Phase 11 site๐Ÿ“ New York Hospital for Special Surgery, New York ยท Tests: ONT01 is a small molecule CD11b modulator. A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G NCT06419205Phase 24 sites๐Ÿ“ Hollywood๐Ÿ“ Lawrenceville๐Ÿ“ Orangeburg Akebia Therapeutics ยท Tests: ADX-097 The Efficacy of Empagliflozin on Kidney Functions in Lupus Nephritis Population NCT07700940Phase 41 site๐Ÿ“ Banฤซ Suwayf Ahmed Yehia Ismail ยท Tests: Empagliflozin (25 Mg Tab) along with standard medical therapy, Placebo and standard of care
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