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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Lymphocytic Leukemia, Chronic

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia NCT05281809Phase 21 site๐Ÿ“ Pittsburgh John Lister ยท Tests: Chimeric Antigen Receptor (CAR) T-Cell Product (Autologous) A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies NCT05908409Phase 1, Phase 211 sites๐Ÿ“ Santander๐Ÿ“ Salamanca๐Ÿ“ Barcelona IDP Discovery Pharma S.L. ยท Tests: IDP-121 Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial NCT06355583Phase 28 sites๐Ÿ“ Birmingham๐Ÿ“ Leeds๐Ÿ“ London Imperial College London ยท Tests: EBX-102, Placebo Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies NCT06508775NA7 sites๐Ÿ“ Berlin๐Ÿ“ Cologne๐Ÿ“ Erlangen Miltenyi Biomedicine GmbH ยท Tests: MB-CART19.1, MB-CART20.1, MB-CART2019.1 Nemtabrutinib and Venetoclax for the Treatment of Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma NCT07557056Phase 21 site๐Ÿ“ Columbus Jennifer Woyach ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Nemtabrutinib Q702 for the Treatment of Patients With Hematologic Malignancies NCT06712810Phase 12 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Axl/Mer/CSF1R Inhibitor Q702, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients NCT05876923NA2 sites๐Ÿ“ Scottsdale๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Cardiopulmonary Exercise Testing, Dual X-ray Absorptiometry, Electronic Health Record Review, Eโ€ฆ Wisconsin Ginseng for Decreasing Cancer Related Fatigue NCT06395441Phase 315 sites๐Ÿ“ Albert Lea๐Ÿ“ Bemidji๐Ÿ“ Brainerd Mayo Clinic ยท Tests: American Ginseng, Placebo Administration, Questionnaire Administration Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia NCT03263572Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Blinatumomab, Cytarabine, Methotrexate, Ponatinib A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab NCT07422337n/a2 sites๐Ÿ“ Little Rock๐Ÿ“ Springdale Arkansas Children's Hospital Research Institute Allo HSCT Using RIC and PTCy for Hematological Diseases NCT05805605Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Peripheral Blood Stem Cell Transplant, Allopurinol 300 MG, Fludarabine, Cyclophosphamide, Bone Marrow Cell Transplant The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen NCT01890486n/a1 site๐Ÿ“ Winston-Salem Wake Forest University Health Sciences Safety Study of CC312 in Adult Patients With Relapsed/Refractory CD19 Positive B-cell Hematologic Malignancies NCT06037018Phase 11 site๐Ÿ“ Tianjin CytoCares Inc ยท Tests: CC312 Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies NCT06904066Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: aldesleukin, cyclophosphamide, fludarabine phosphate, Individual Patient TCR-Transduced PBL, TruSight Oncology (TSO) 500 Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies NCT07648264Phase 360 sites๐Ÿ“ Orange๐Ÿ“ Denver๐Ÿ“ Coral Springs CSL Behring ยท Tests: IgPro20 Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors NCT05643235NA1 site๐Ÿ“ New Hyde Park Northwell Health ยท Tests: Medtronic LINQ-2 Insertable Cardiac Monitor (ILR) A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma NCT06588478Phase 2131 sites๐Ÿ“ Chandler๐Ÿ“ Duarte๐Ÿ“ Irvine Loxo Oncology, Inc. ยท Tests: Pirtobrutinib Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma NCT06757647Phase 21 site๐Ÿ“ Columbus Seema Bhat ยท Tests: Acalabrutinib, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL) NCT00923507n/a1 site๐Ÿ“ Bethesda National Heart, Lung, and Blood Institute (NHLBI) The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies NCT04329728Phase 1, Phase 211 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles AVM Biotechnology Inc ยท Tests: AVM0703 Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV) NCT07509151Phase 344 sites๐Ÿ“ La Jolla๐Ÿ“ Denver๐Ÿ“ New Haven AstraZeneca ยท Tests: Surovatamig Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL) NCT06644183Phase 1, Phase 21 site๐Ÿ“ Boston Jennifer R. Brown, MD, PhD ยท Tests: Roginolisib, Venetoclax, Rituximab Treatment of Chinese Participants With B-Cell Malignancies With BGB-16673, a Bruton Tyrosine Kinase-Targeted Protein-Degrader NCT05294731Phase 1, Phase 229 sites๐Ÿ“ Bengbu๐Ÿ“ Hefei๐Ÿ“ Beijing BeOne Medicines ยท Tests: Tacabrutideg A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies NCT06528301Phase 19 sites๐Ÿ“ Duarte๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Umoja Biopharma ยท Tests: UB-VV111, rapamycin Mosunetuzumab for CLL MRD Clearance NCT07052695Phase 1, Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Boston Inhye Ahn ยท Tests: Mosunetuzumab, Ibrutinib, Acalabrutinib, Zanubrutinib, Pirtobrutinib CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia NCT04704323Phase 14 sites๐Ÿ“ Boston๐Ÿ“ Durham๐Ÿ“ Madrid Catapult Therapeutics ยท Tests: CAP-100 A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies NCT06564038Phase 1, Phase 265 sites๐Ÿ“ Boston๐Ÿ“ Hackensack๐Ÿ“ New Brunswick AstraZeneca ยท Tests: Surovatamig, Prednisone (or equivalent), Rituximab, Cyclophosphamide, Vincristine A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL NCT05197192Phase 330 sites๐Ÿ“ Bad Saarow๐Ÿ“ Berlin๐Ÿ“ Bremen German CLL Study Group ยท Tests: Obinutuzumab, Venetoclax, Acalabrutinib A Study of Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated With Lisocabtagene Maraleucel in the Post-Marketing Setting NCT06788639n/a1 site๐Ÿ“ Milwaukee Juno Therapeutics, Inc., a Bristol-Myers Squibb Company ยท Tests: Lisocabtagene maraleucel A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ Phoenix Center for International Blood and Marrow Transplant Researโ€ฆ ยท Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
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