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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Brain Glioma

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA NCT01269853Phase 1, Phase 21 site๐Ÿ“ New York Northwell Health ยท Tests: Bevacizumab, Bevacizumab Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site๐Ÿ“ China The Third Affiliated hospital of Zhejiang Chinese Medical Uโ€ฆ ยท Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors NCT04908709NA3 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Magnetic Resonance Spectroscopic Imaging, Proton Therapy Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloudยฎ Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites๐Ÿ“ Paris๐Ÿ“ Paris๐Ÿ“ Villejuif Assistance Publique - Hรดpitaux de Paris ยท Tests: SonoCloudยฎ (9 transducers) Atovaquone Combined With Radiation in Children With Malignant Brain Tumors NCT06624371Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Atovaquone, Radiation Therapy Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: LMP744, Conventional Surgery or Biopsy Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site๐Ÿ“ New York Jeffrey N. Bruce ยท Tests: Topotecan Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases NCT05474573NA1 site๐Ÿ“ Moscow Sklifosovsky Institute of Emergency Care ยท Tests: Combined ultrasound and fluorescence-guided brain tumor resection, Fluorescence-guided brain tumor resection FearLess in NeuroOncology NCT06989086NA1 site๐Ÿ“ Richmond Virginia Commonwealth University ยท Tests: Fearless in Neuro-Oncology Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site๐Ÿ“ Miami Florida International University ยท Tests: Functional Precision Medicine SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON) NCT05254197n/a1 site๐Ÿ“ Seoul Seoul National University Hospital A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Gainesville University of Florida ยท Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liโ€ฆ Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site๐Ÿ“ Atlanta Emory University ยท Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery NCT03510208Phase 1, Phase 21 site๐Ÿ“ Palo Alto Stanford University ยท Tests: Near-Infrared Fluorescence Imaging, Panitumumab, Panitumumab-IRDye800, POINPOINT-IR9000 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours NCT06630260Phase 1, Phase 23 sites๐Ÿ“ Cambridge๐Ÿ“ Sutton๐Ÿ“ Sutton Institute of Cancer Research, United Kingdom ยท Tests: Avutometinib, Defactinib, Temozolomide SIMPLIFication of Care Pathways for Patients With Rare Brain Tumors Through Artificial Intelligence NCT06878469NA2 sites๐Ÿ“ Milan๐Ÿ“ Lโ€™Aquila Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta ยท Tests: RehaCom DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. NCT05770544Phase 2, Phase 327 sites๐Ÿ“ Belfast๐Ÿ“ Birmingham๐Ÿ“ Birmingham Cancer Research UK ยท Tests: Entrectinib Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection NCT06018363Phase 1, Phase 21 site๐Ÿ“ Suzhou Dushu Lake Hospital Affiliated to Soochow University ยท Tests: Allogenic B7-H3 CAR-ฮณฮดT cell(QH104) Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma NCT05954858NA1 site๐Ÿ“ New York Northwell Health ยท Tests: Tissue autograft of pedicled temporoparietal fascial (TPF) or pericranial flap to bypass the blood brain barrier (BBB) HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites๐Ÿ“ Birmingham๐Ÿ“ St Louis๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: G207 Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG NCT05555550EARLY Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: 18F-Fluciclovine Mapping of Electrical Properties in the Brain NCT06470711n/a1 site๐Ÿ“ Scottsdale Mayo Clinic ยท Tests: Non-Interventional Study Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss NCT06810544Phase 1, Phase 215 sites๐Ÿ“ Scottsdale๐Ÿ“ Irvine๐Ÿ“ Los Angeles Tango Therapeutics, Inc. ยท Tests: TNG456, abemaciclib Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site๐Ÿ“ New York Memorial Sloan Kettering Cancer Center ยท Tests: MRI and advanced MRI sequences The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma NCT06273176n/a8 sites๐Ÿ“ San Francisco๐Ÿ“ Boston๐Ÿ“ Leuven Erasmus Medical Center ยท Tests: Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia withoโ€ฆ Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors NCT06914479Phase 11 site๐Ÿ“ Ann Arbor University of Michigan Rogel Cancer Center ยท Tests: Ad-hCMV-Flt3L, Ad-hCMV-TK, Biospecimen Collection, Magnetic Resonance Imaging, Survey Administration 18F-Fluciclovine PET-MRI in High-grade Glioma NCT05553041EARLY Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: 18F-Fluciclovine PET-MRI NeuroPathways Intervention for Brain Tumor Patients NCT05976490NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Information and Support Intervention, Usual supportive care 000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations NCT05588141Phase 1, Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Zotiraciclib
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