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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Neoplasm of Brain

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA NCT01269853Phase 1, Phase 21 site๐Ÿ“ New York Northwell Health ยท Tests: Bevacizumab, Bevacizumab Atamparib in Patients With Advanced Solid Tumors NCT07374419Phase 1, Phase 21 site๐Ÿ“ Shanghai Nerviano Medical Sciences (Shanghai) Ltd. ยท Tests: atamparib escalation levels, atamparib RP2D Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site๐Ÿ“ China The Third Affiliated hospital of Zhejiang Chinese Medical Uโ€ฆ ยท Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors NCT04908709NA3 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Magnetic Resonance Spectroscopic Imaging, Proton Therapy Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloudยฎ Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites๐Ÿ“ Paris๐Ÿ“ Paris๐Ÿ“ Villejuif Assistance Publique - Hรดpitaux de Paris ยท Tests: SonoCloudยฎ (9 transducers) Atovaquone Combined With Radiation in Children With Malignant Brain Tumors NCT06624371Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Atovaquone, Radiation Therapy An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial NCT07278440NA1 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Electronic Health Record Review, Magnetic Resonance Imaging, Questionnaire Administration, Resistance Training An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou๐Ÿ“ Hangzhou Beijing Tide Pharmaceutical Co., Ltd ยท Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors NCT05831631n/a1 site๐Ÿ“ Milan Pietro Mortini, MD, Prof. ยท Tests: Circulating leukocytes immunophenotype, Tumor sampling Cancer Genetic Testing in Ethnic Populations NCT04475640NA2 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Biospecimen Collection, Genetic Testing Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease NCT06092125n/a1 site๐Ÿ“ Beijing Xuanwu Hospital, Beijing ยท Tests: PET/MR The Impact of Paramedic Training in Simulation on the Experience of Patients Treated for Malignant Brain Tumors in Neurosurgery (IPSIMANON) NCT06962215NA11 sites๐Ÿ“ Brest๐Ÿ“ Amiens๐Ÿ“ Angers University Hospital, Brest ยท Tests: Paramedic training Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis NCT07339085NA1 site๐Ÿ“ Los Angeles Jonsson Comprehensive Cancer Center ยท Tests: Advanced Magnetic Resonance Imaging, Biospecimen Collection, Magnetic Resonance Imaging Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: LMP744, Conventional Surgery or Biopsy A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma NCT06736613Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Cerebral Spinal Fluid ctDNA Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site๐Ÿ“ New York Jeffrey N. Bruce ยท Tests: Topotecan Concurrent Fluorescence and Sonographically Guided Eradication of High-grade Gliomas and Metastases NCT05474573NA1 site๐Ÿ“ Moscow Sklifosovsky Institute of Emergency Care ยท Tests: Combined ultrasound and fluorescence-guided brain tumor resection, Fluorescence-guided brain tumor resection The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study NCT04075305n/a18 sites๐Ÿ“ Pittsburgh๐Ÿ“ Houston๐Ÿ“ Milwaukee UMC Utrecht ยท Tests: Radiation therapy FearLess in NeuroOncology NCT06989086NA1 site๐Ÿ“ Richmond Virginia Commonwealth University ยท Tests: Fearless in Neuro-Oncology Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors NCT02754544NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Direct Electrocortical Stimulation, Electrocorticography SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial NCT05222620Phase 27 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville๐Ÿ“ Albert Lea Mayo Clinic ยท Tests: Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic Radiosurgery, Magnetic Resonance Imaging Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases NCT06328686EARLY Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Arginine, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Spectroscopy Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors NCT03750227Phase 34 sites๐Ÿ“ Scottsdale๐Ÿ“ Jacksonville๐Ÿ“ Bethesda Mayo Clinic ยท Tests: Conventional Surgery, Questionnaire Administration, Stereotactic Radiosurgery, Computed Tomography, Magnetic Resonance โ€ฆ Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site๐Ÿ“ Miami Florida International University ยท Tests: Functional Precision Medicine A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases NCT04511013Phase 2331 sites๐Ÿ“ Birmingham๐Ÿ“ Fairhope๐Ÿ“ Mobile SWOG Cancer Research Network ยท Tests: Binimetinib, Encorafenib, Ipilimumab, Nivolumab SeOuL cOhort of Brain Tumor MONitoring Study (SOLOMON) NCT05254197n/a1 site๐Ÿ“ Seoul Seoul National University Hospital A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM) NCT04573140Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Gainesville University of Florida ยท Tests: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liโ€ฆ Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site๐Ÿ“ Atlanta Emory University ยท Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration Surgical Resection of Latent Brain Tumors Prior to Recurrence NCT04810871NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Brain Surgery
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