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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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21 recruiting trials

for Malignant Pleural Effusions

Safety and Efficacy of NK510 to Treat NSCLC NCT06097962EARLY Phase 11 site📍 Nanjing Base Therapeutics (Shanghai) Co., Ltd. · Tests: NK510, Tislelizumab，atezolizumab or sugemalimab, NK510, systemic therapy as selected by the investigator ARMSTRONG - Air entRainMent vS sTandard tReatment in nOn-expandable luNG NCT06959719NA1 site📍 Cambridge Cambridge University Hospitals NHS Foundation Trust · Tests: Air Entrainment - intentional introduction of the atmospheric air into the pleural space. Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion NCT07726784NA2 sites📍 Kuala Lumpur📍 Cheras National University of Malaysia · Tests: Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study. NCT04806412NA1 site📍 Næstved Naestved Hospital · Tests: meassurement of PD-L1, ALK, EGFR Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion NCT06184321EARLY Phase 12 sites📍 Baltimore📍 Houston M.D. Anderson Cancer Center · Tests: Alteplase, Placebo Administration A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion NCT06740019Phase 11 site📍 Beijing Jemincare · Tests: JMKX000197, Tube thoracostomy drainage UNC Pleural Fluid Registry NCT05620329n/a1 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors NCT07443020Phase 11 site📍 Pittsburgh Allegheny Singer Research Institute (also known as Alleghen… · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 (IL-2) A Study of MT027 in Patients with Pleural Malignant Tumors NCT06726564Phase 11 site📍 Beijing Suzhou Maximum Bio-tech Co., Ltd. · Tests: MT027 cells suspension Dual-targeting VEGFR1 and PD-L1 CAR-T for Pleural, Peritoneal, or Leptomeningeal Metastases NCT05477927Phase 11 site📍 Chengdu Sichuan University · Tests: Dual-targeting VEGFR1/PD-L1 CAR-T cells Feasibility of Ambulatory Talc. Pleurodesis NCT06682936NA1 site📍 Stockton-on-Tees David Rollins · Tests: ambulatory chest drain and talc pleurodesis A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC NCT05543330Phase 1, Phase 21 site📍 Hangzhou Wuhan YZY Biopharma Co., Ltd. · Tests: M701 pleural infusion, Pleural drainage, Cisplatin pleural infusion Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound NCT07147270NA1 site📍 Cairo Ain Shams University · Tests: side to side and front to back rotation 30 minutes each First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. NCT06946498NA1 site📍 Athens National and Kapodistrian University of Athens · Tests: Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies Ex Vivo Drug Response Profiling and Outcome Prediction in Lung Adenocarcinoma NCT07636252n/a1 site📍 Ramat Gan Sheba Medical Center · Tests: Non-Interventional Study A Phase II Study of AK112 (PD1/VEGF Bispecific) in Combination with Chemotherapy in Patients with NSCLC NCT06769295Phase 21 site📍 Chengdu Sichuan University · Tests: AK112 Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions NCT03465774n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Doxycycline, Indwelling Catheter, Quality-of-Life Assessment, Questionnaire Administration, Survey Administration Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer NCT06016179Phase 11 site📍 Pittsburgh Allegheny Singer Research Institute (also known as Alleghen… · Tests: Tocilizumab Dual-targeting HER2 and PD-L1 CAR-T for Solid Tumors NCT04684459EARLY Phase 11 site📍 Chengdu Sichuan University · Tests: Dual-targeting HER2 and PD-L1 CAR-T cells Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease NCT07192900Phase 11 site📍 Pittsburgh David Bartlett, MD · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion NCT07332858Phase 1, Phase 21 site📍 Beijing Gang Hou · Tests: Intrapleural administration of TolueneSulfonamide, Intrapleural administration of normal saline injection
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