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30 recruiting trials

for Metabolic Associated Steatotic Liver Disease

Accurate Point of Care Liver Disease Diagnostics (Phase 2) NCT07518784n/a1 site๐Ÿ“ La Jolla University of California, San Diego ยท Tests: LiverScopeยฎ exam, MR exam, Blood draw, Body measurements, Questionnaire Digital Early Warning System for Acute Lung Injury in Liver Surgery NCT07070362n/a4 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing Beijing Tsinghua Chang Gung Hospital Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Associated Membranes ) Alteration in Patients Undergoing Bariatric Surgery - MAMBA NCT06868992n/a2 sites๐Ÿ“ Lyon๐Ÿ“ Pierre-Bรฉnite Hospices Civils de Lyon ยท Tests: Bariatric surgery (Sleeve Gastrectomy or Gastric Bypass) Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial NCT07193927Phase 21 site๐Ÿ“ Girona AB Biotics, SA ยท Tests: Lactiplantibacillus plantarum Probiotic Mixture, Placebo comparator containing maltodextrin Taiwan Green Propolis for Blood Lipids and Body Fat in Patients With MASLD NCT07692438NA1 site๐Ÿ“ Dalin Taipei Medical University ยท Tests: Taiwan green propolis capsule, Placebo capsule Implementing Food Referrals for Equity and Sustained Health NCT06661538Phase 22 sites๐Ÿ“ La Jolla๐Ÿ“ San Diego University of California, San Diego ยท Tests: Food Security Screening & Referral Program Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH) NCT07631637Phase 216 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: ALN-CIDEB, Placebo Clinical Profile of Patients With MASLD in Kazakhstan and Clinical Effectiveness of Ursosan in Almaty NCT07889999n/a7 sites๐Ÿ“ Aktobe๐Ÿ“ Almaty๐Ÿ“ Almaty Kazakh Association of Internal Medicine Specialists Time-restricted Feeding in MASLD NCT07530809NA1 site๐Ÿ“ Homburg Universitรคt des Saarlandes ยท Tests: time-restricted feeding in a 5:2 regimen SMART Diets for MASLD NCT07459504Phase 21 site๐Ÿ“ Grand Rapids Michigan State University ยท Tests: Essential Amino Acids Supplementation intervention, Low sugar diet Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study) NCT07481734Phase 21 site๐Ÿ“ Shenzhen Hudson Biotech ยท Tests: Tesamorelin, Placebo, Standardized lifestyle counseling A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Metabolic Alcohol-Related Liver Disease NCT07450144NA1 site๐Ÿ“ Hong Kong The University of Hong Kong ยท Tests: LLM-based chatbot, Telephone counseling, Alcohol Brief Intervention Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly NCT07068191NA1 site๐Ÿ“ Tyumen Phenomen Pharma ยท Tests: Dietary supplement "Gepaktiv", UDCA (Ursodeoxycholic acid), Ademetionine UNMASK: Unveiling the Pathobiology of Metabolic Dysfunction-Associated Steatotic Liver Disease for the Discovery of Novel Therapeutics and Biomarkers NCT07652151NA3 sites๐Ÿ“ Roma๐Ÿ“ Seville๐Ÿ“ Ankara Fundaciรณn Pรบblica Andaluza para la gestiรณn de la Investigacโ€ฆ ยท Tests: Multimodal lifestyle intervention Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease NCT07058155Phase 41 site๐Ÿ“ Cleveland The Cleveland Clinic ยท Tests: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), โ€ฆ A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) NCT05648214Phase 1, Phase 26 sites๐Ÿ“ Glendale๐Ÿ“ Los Angeles๐Ÿ“ Miami Regeneron Pharmaceuticals ยท Tests: ALN-PNP, Placebo (PB) Cardiovascular Risk Assessment and Coronary Calcium Score in Thai MASLD Patients NCT07865936n/a1 site๐Ÿ“ Bangkok Watcharasak Chotiyaputta Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease NCT04873258n/a1 site๐Ÿ“ London Richmond Research Institute ยท Tests: Bioimpedence Vector Analysis Efficacy and Safety of Rifaximin-ฮฑ in Treating MASLD NCT07381257EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: Rifaximin-ฮฑ (Alfa Wassermann S.p.A., Italy) Spleen Stiffness Measurement for the Detection of Advanced Fibrosis NCT07440511n/a1 site๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) NCT07330830n/a3 sites๐Ÿ“ Cayenne๐Ÿ“ Pointe-ร -Pitre๐Ÿ“ Saint-Denis Centre Hospitalier Universitaire de la Guadeloupe A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) NCT06318169Phase 3370 sites๐Ÿ“ Birmingham๐Ÿ“ Chandler๐Ÿ“ Flagstaff Hoffmann-La Roche ยท Tests: Pegozafermin, Placebo Food Insecurity and MASLD: A Fruit and Vegetable Intervention Study NCT07091539NA1 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Fruit/vegetable vouchers Stimulating Fat Tissue Storage With Niacin to Reduce Fat Accumulation in the Liver. NCT06843148NA1 site๐Ÿ“ Sherbrooke Universitรฉ de Sherbrooke ยท Tests: Niacin (250mg), Placebo Oral Tablet Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians NCT07682363n/a1 site๐Ÿ“ Beijing Novo Nordisk A/S ยท Tests: No treatment is given A Study of Efimosfermin Alfa in Adults With Hepatic Impairment NCT07358546Phase 13 sites๐Ÿ“ Rialto๐Ÿ“ Tampa๐Ÿ“ San Antonio GlaxoSmithKline ยท Tests: Efimosfermin alfa Quantitative Ultrasound to Assess Steatotic Liver Disease in Children NCT06706856n/a1 site๐Ÿ“ La Jolla University of California, San Diego ยท Tests: MR exam, US exam, Blood draw, Physical measurements, Questionnaires The Establishment of Hong Kong Diabetes Steatotic Liver Disease Register NCT07437157n/a1 site๐Ÿ“ Hong Kong Chinese University of Hong Kong ยท Tests: No intervention (observational study) Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity NCT07378072NA9 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Dijon Nantes University Hospital ยท Tests: Time Restricted Eating, Usual care only A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition NCT05519475Phase 271 sites๐Ÿ“ Flagstaff๐Ÿ“ Peoria๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: ALN-HSD, Placebo
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